TY - JOUR
T1 - Food-aversion conditioning in Japanese monkeys (Macaca fuscata)
T2 - suppression of key-pressing
AU - Matsuzawa, Tetsuro
AU - Hasegawa, Yoshinori
N1 - Funding Information:
t This study was supported by Grants 556106 and 56560159 from the Japanese Ministry of Education to T. Matsuzawa. z We wish to thank S. Gotoh for his clinical assistance, and K. Wada and S. Azuma for valuable suggestions.
PY - 1982/11
Y1 - 1982/11
N2 - Monkeys were trained in a Skinner box to press a key for standard food pellets on a fixed-ratio 10 schedule for 30 min. When stable responding had been achieved, two novel foods (almond nuts and marshmallows) were introduced. In the conditioning sessions on the odd-number days, pressing a key delivered one of the two novel foods as the to-be-conditioned target food, and each monkey was injected cyclophosphamide (4 mg/kg) intravenously in the home cage 10 min after the end of the session. In the control sessions on the even-number days, the monkeys earned the other food, and were never injected. As the conditioning was repeated, the monkeys eventually stopped key-pressing for the target food in the conditioning sessions, but continued to work for and eat the other food in the control sessions.
AB - Monkeys were trained in a Skinner box to press a key for standard food pellets on a fixed-ratio 10 schedule for 30 min. When stable responding had been achieved, two novel foods (almond nuts and marshmallows) were introduced. In the conditioning sessions on the odd-number days, pressing a key delivered one of the two novel foods as the to-be-conditioned target food, and each monkey was injected cyclophosphamide (4 mg/kg) intravenously in the home cage 10 min after the end of the session. In the control sessions on the even-number days, the monkeys earned the other food, and were never injected. As the conditioning was repeated, the monkeys eventually stopped key-pressing for the target food in the conditioning sessions, but continued to work for and eat the other food in the control sessions.
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U2 - 10.1016/S0163-1047(82)90939-6
DO - 10.1016/S0163-1047(82)90939-6
M3 - Article
C2 - 7183321
AN - SCOPUS:0020307212
VL - 36
SP - 298
EP - 303
JO - Communications in behavioral biology. Part A: [Original articles]
JF - Communications in behavioral biology. Part A: [Original articles]
SN - 1074-7427
IS - 3
ER -