Fluorescence study on the domain formation of N-dodecanoyl-L-tryptophan within a liposome membrane

Kazuma Yasuhara, Toshinori Shimanouchi, Hiroshi Umakoshi, Ryoichi Kuboi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The aggregation behavior of N-dodecanoyl-L-tryptophan within a liposome membrane was investigated by fluorescence spectroscopy. Liposomes with a mean diameter of 100 nm, formed from either 1-2-dilauroyl-sn-glycero-3-phosphocholine, 1-2-myristoyl-sn-glycero-3-phosphocholine, or 1-2-palmitoyl-sn-glycero-3-phosphocholine, were used. Fluorescence measurements indicate that the sodium salt of N-dodecanoyl-L-tryptophan forms domains with the liposome membranes below the main phase transition temperature, Tm. Above Tm, the molecules are homogeneously dispersed in the liquid crystalline state of the membranes.

Original languageEnglish
Pages (from-to)239-243
Number of pages5
JournalColloid and Polymer Science
Volume285
Issue number2
DOIs
Publication statusPublished - Nov 2006
Externally publishedYes

Fingerprint

Phosphorylcholine
Liposomes
tryptophan
Tryptophan
Fluorescence
membranes
Membranes
fluorescence
Fluorescence spectroscopy
Superconducting transition temperature
Agglomeration
Salts
Phase transitions
Sodium
transition temperature
sodium
Crystalline materials
salts
Molecules
Liquids

Keywords

  • Aminoacid-type surfactant
  • Domain formation
  • Liposome
  • Phase transition
  • Tryptophan fluorescence

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Polymers and Plastics
  • Materials Chemistry
  • Colloid and Surface Chemistry

Cite this

Fluorescence study on the domain formation of N-dodecanoyl-L-tryptophan within a liposome membrane. / Yasuhara, Kazuma; Shimanouchi, Toshinori; Umakoshi, Hiroshi; Kuboi, Ryoichi.

In: Colloid and Polymer Science, Vol. 285, No. 2, 11.2006, p. 239-243.

Research output: Contribution to journalArticle

Yasuhara, Kazuma ; Shimanouchi, Toshinori ; Umakoshi, Hiroshi ; Kuboi, Ryoichi. / Fluorescence study on the domain formation of N-dodecanoyl-L-tryptophan within a liposome membrane. In: Colloid and Polymer Science. 2006 ; Vol. 285, No. 2. pp. 239-243.
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