TY - GEN
T1 - Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides
AU - Stasio, Nicolino
AU - Shibukawa, Atsushi
AU - Papadopoulos, Ioannis N.
AU - Farahi, Salma
AU - Simandoux, Olivier
AU - Huignard, Jean Pierre
AU - Bossy, Emmanuel
AU - Moser, Christophe
AU - Psaltis, Demetri
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Endoscopy can be used to obtain high-resolution images at large depths in biological tissues. Usually endoscopic devices have a diameter ranging from 1 to few millimeters. Using digital phase conjugation, it is possible to adapt ultrathin multimode fibers to endoscopic purposes. Recently, we demonstrated that a 330 μm diameter, water-filled silica capillary waveguide can guide high frequency ultrasound waves through a 3 cm thick fat layer, allowing optical resolution photoacoustic imaging. Here we demonstrate that using digital phase conjugation, the same water-filled capillary waveguide (3 cm long) can be used as an endoscopic probe to obtain both fluorescence and optical resolution photoacoustic imaging, with no optical or acoustic elements at the tip of the waveguide. We study the consequences of using digital phase conjugation combined with a capillary waveguide and we conclude with possible future improvements of our endoscopic approach.
AB - Endoscopy can be used to obtain high-resolution images at large depths in biological tissues. Usually endoscopic devices have a diameter ranging from 1 to few millimeters. Using digital phase conjugation, it is possible to adapt ultrathin multimode fibers to endoscopic purposes. Recently, we demonstrated that a 330 μm diameter, water-filled silica capillary waveguide can guide high frequency ultrasound waves through a 3 cm thick fat layer, allowing optical resolution photoacoustic imaging. Here we demonstrate that using digital phase conjugation, the same water-filled capillary waveguide (3 cm long) can be used as an endoscopic probe to obtain both fluorescence and optical resolution photoacoustic imaging, with no optical or acoustic elements at the tip of the waveguide. We study the consequences of using digital phase conjugation combined with a capillary waveguide and we conclude with possible future improvements of our endoscopic approach.
KW - Wavefront shaping
KW - capillary waveguides
KW - digital holography
KW - digital phase conjugation
KW - endoscopic imaging
KW - fluorescence imaging
KW - photoacoustic imaging
UR - http://www.scopus.com/inward/record.url?scp=84982966385&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84982966385&partnerID=8YFLogxK
U2 - 10.1117/12.2213303
DO - 10.1117/12.2213303
M3 - Conference contribution
AN - SCOPUS:84982966385
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Adaptive Optics and Wavefront Control for Biological Systems II
A2 - Gigan, Sylvain
A2 - Bifano, Thomas G.
A2 - Kubby, Joel
PB - SPIE
T2 - Adaptive Optics and Wavefront Control for Biological Systems II
Y2 - 13 February 2016 through 15 February 2016
ER -