Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides

Nicolino Stasio; Atsushi Shibukawa; Ioannis N. Papadopoulos; Salma Farahi; Olivier Simandoux; Jean Pierre Huignard; Emmanuel Bossy; Christophe Moser; Demetri Psaltis

doi:10.1117/12.2213303

Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides

Nicolino Stasio, Atsushi Shibukawa, Ioannis N. Papadopoulos, Salma Farahi, Olivier Simandoux, Jean Pierre Huignard, Emmanuel Bossy, Christophe Moser, Demetri Psaltis

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Endoscopy can be used to obtain high-resolution images at large depths in biological tissues. Usually endoscopic devices have a diameter ranging from 1 to few millimeters. Using digital phase conjugation, it is possible to adapt ultrathin multimode fibers to endoscopic purposes. Recently, we demonstrated that a 330 μm diameter, water-filled silica capillary waveguide can guide high frequency ultrasound waves through a 3 cm thick fat layer, allowing optical resolution photoacoustic imaging. Here we demonstrate that using digital phase conjugation, the same water-filled capillary waveguide (3 cm long) can be used as an endoscopic probe to obtain both fluorescence and optical resolution photoacoustic imaging, with no optical or acoustic elements at the tip of the waveguide. We study the consequences of using digital phase conjugation combined with a capillary waveguide and we conclude with possible future improvements of our endoscopic approach.

Original language	English
Title of host publication	Adaptive Optics and Wavefront Control for Biological Systems II
Editors	Sylvain Gigan, Thomas G. Bifano, Joel Kubby
Publisher	SPIE
ISBN (Electronic)	9781628419511
DOIs	https://doi.org/10.1117/12.2213303
Publication status	Published - Jan 1 2016
Externally published	Yes
Event	Adaptive Optics and Wavefront Control for Biological Systems II - San Francisco, United States Duration: Feb 13 2016 → Feb 15 2016

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9717
ISSN (Print)	1605-7422

Other

Other	Adaptive Optics and Wavefront Control for Biological Systems II
Country	United States
City	San Francisco
Period	2/13/16 → 2/15/16

Keywords

Wavefront shaping
capillary waveguides
digital holography
digital phase conjugation
endoscopic imaging
fluorescence imaging
photoacoustic imaging

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

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Stasio, N., Shibukawa, A., Papadopoulos, I. N., Farahi, S., Simandoux, O., Huignard, J. P., Bossy, E., Moser, C., & Psaltis, D. (2016). Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides. In S. Gigan, T. G. Bifano, & J. Kubby (Eds.), Adaptive Optics and Wavefront Control for Biological Systems II [97171H] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9717). SPIE. https://doi.org/10.1117/12.2213303

Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides. / Stasio, Nicolino; Shibukawa, Atsushi; Papadopoulos, Ioannis N.; Farahi, Salma; Simandoux, Olivier; Huignard, Jean Pierre; Bossy, Emmanuel; Moser, Christophe; Psaltis, Demetri.

Adaptive Optics and Wavefront Control for Biological Systems II. ed. / Sylvain Gigan; Thomas G. Bifano; Joel Kubby. SPIE, 2016. 97171H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9717).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Stasio, N, Shibukawa, A, Papadopoulos, IN, Farahi, S, Simandoux, O, Huignard, JP, Bossy, E, Moser, C & Psaltis, D 2016, Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides. in S Gigan, TG Bifano & J Kubby (eds), Adaptive Optics and Wavefront Control for Biological Systems II., 97171H, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9717, SPIE, Adaptive Optics and Wavefront Control for Biological Systems II, San Francisco, United States, 2/13/16. https://doi.org/10.1117/12.2213303

Stasio N, Shibukawa A, Papadopoulos IN, Farahi S, Simandoux O, Huignard JP et al. Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides. In Gigan S, Bifano TG, Kubby J, editors, Adaptive Optics and Wavefront Control for Biological Systems II. SPIE. 2016. 97171H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2213303

Stasio, Nicolino ; Shibukawa, Atsushi ; Papadopoulos, Ioannis N. ; Farahi, Salma ; Simandoux, Olivier ; Huignard, Jean Pierre ; Bossy, Emmanuel ; Moser, Christophe ; Psaltis, Demetri. / Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides. Adaptive Optics and Wavefront Control for Biological Systems II. editor / Sylvain Gigan ; Thomas G. Bifano ; Joel Kubby. SPIE, 2016. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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AU - Simandoux, Olivier

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