Flow injection analysis of ascorbic acid using carriers modified with metal-porphine as oxidative solid catalyses

Akimasa Iwado; Masaki Mifune; Hiromichi Akizawa; Noriko Motohashi; Yutaka Saito

doi:10.1016/S0731-7085(02)00536-8

Flow injection analysis of ascorbic acid using carriers modified with metal-porphine as oxidative solid catalyses

Akimasa Iwado, Masaki Mifune, Hiromichi Akizawa, Noriko Motohashi, Yutaka Saito

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

To investigate one of practical applications of the supports modified with metal-porphines as artificial solid-catalysts, columns into which the supports were packed were supplied to catalytic columns for a flow injection analysis (FIA) system for determination of ascorbic acid (AsA) by the following reactions:AsA+O₂→dehydoroAsA+H₂O₂,H ₂O₂+chromogen→2H₂O+Dye.Among the columns tested, the column containing silica gels modified with Co-tetrakis(carboxyphenyl)porphine catalyzed most rapidly the oxidation reaction of AsA that is accompanied by the formation of hydrogen peroxide. The resulting hydrogen peroxide was determined by FIA system equipped with the column containing glass beads modified with Mn-tetrakis(carboxyphenyl)porphine, which gave a linear calibration curve and large peak-areas of the range corresponding to AsA concentration between 0.2 and 10 μmol/ml. The results indicated that some supports modified with metal-porphine would be applicable to the FIA for AsA as the solid catalyses which function as if the immobilized enzymes.

Original language	English
Pages (from-to)	1923-1928
Number of pages	6
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	30
Issue number	6
DOIs	https://doi.org/10.1016/S0731-7085(02)00536-8
Publication status	Published - Jan 15 2003

Keywords

Ascorbic acid
Catalysis
Flow injection analysis
Metal-porphine
Mimesis of enzyme
Modified carriers

ASJC Scopus subject areas

Analytical Chemistry
Pharmaceutical Science
Drug Discovery
Spectroscopy
Clinical Biochemistry

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title = "Flow injection analysis of ascorbic acid using carriers modified with metal-porphine as oxidative solid catalyses",

abstract = "To investigate one of practical applications of the supports modified with metal-porphines as artificial solid-catalysts, columns into which the supports were packed were supplied to catalytic columns for a flow injection analysis (FIA) system for determination of ascorbic acid (AsA) by the following reactions:AsA+O2→dehydoroAsA+H2O2,H 2O2+chromogen→2H2O+Dye.Among the columns tested, the column containing silica gels modified with Co-tetrakis(carboxyphenyl)porphine catalyzed most rapidly the oxidation reaction of AsA that is accompanied by the formation of hydrogen peroxide. The resulting hydrogen peroxide was determined by FIA system equipped with the column containing glass beads modified with Mn-tetrakis(carboxyphenyl)porphine, which gave a linear calibration curve and large peak-areas of the range corresponding to AsA concentration between 0.2 and 10 μmol/ml. The results indicated that some supports modified with metal-porphine would be applicable to the FIA for AsA as the solid catalyses which function as if the immobilized enzymes.",

keywords = "Ascorbic acid, Catalysis, Flow injection analysis, Metal-porphine, Mimesis of enzyme, Modified carriers",

author = "Akimasa Iwado and Masaki Mifune and Hiromichi Akizawa and Noriko Motohashi and Yutaka Saito",

note = "Funding Information: The authors thank K. Hirose (Nee Abe) and T. Nakamura for their technical supports. This work was supported by a Grant-in-Aid for Sciences Research (#11672142) from Japan Society for Promotion of Science.",

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doi = "10.1016/S0731-7085(02)00536-8",

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T1 - Flow injection analysis of ascorbic acid using carriers modified with metal-porphine as oxidative solid catalyses

AU - Iwado, Akimasa

AU - Mifune, Masaki

AU - Akizawa, Hiromichi

AU - Motohashi, Noriko

AU - Saito, Yutaka

N1 - Funding Information: The authors thank K. Hirose (Nee Abe) and T. Nakamura for their technical supports. This work was supported by a Grant-in-Aid for Sciences Research (#11672142) from Japan Society for Promotion of Science.

PY - 2003/1/15

Y1 - 2003/1/15

N2 - To investigate one of practical applications of the supports modified with metal-porphines as artificial solid-catalysts, columns into which the supports were packed were supplied to catalytic columns for a flow injection analysis (FIA) system for determination of ascorbic acid (AsA) by the following reactions:AsA+O2→dehydoroAsA+H2O2,H 2O2+chromogen→2H2O+Dye.Among the columns tested, the column containing silica gels modified with Co-tetrakis(carboxyphenyl)porphine catalyzed most rapidly the oxidation reaction of AsA that is accompanied by the formation of hydrogen peroxide. The resulting hydrogen peroxide was determined by FIA system equipped with the column containing glass beads modified with Mn-tetrakis(carboxyphenyl)porphine, which gave a linear calibration curve and large peak-areas of the range corresponding to AsA concentration between 0.2 and 10 μmol/ml. The results indicated that some supports modified with metal-porphine would be applicable to the FIA for AsA as the solid catalyses which function as if the immobilized enzymes.

AB - To investigate one of practical applications of the supports modified with metal-porphines as artificial solid-catalysts, columns into which the supports were packed were supplied to catalytic columns for a flow injection analysis (FIA) system for determination of ascorbic acid (AsA) by the following reactions:AsA+O2→dehydoroAsA+H2O2,H 2O2+chromogen→2H2O+Dye.Among the columns tested, the column containing silica gels modified with Co-tetrakis(carboxyphenyl)porphine catalyzed most rapidly the oxidation reaction of AsA that is accompanied by the formation of hydrogen peroxide. The resulting hydrogen peroxide was determined by FIA system equipped with the column containing glass beads modified with Mn-tetrakis(carboxyphenyl)porphine, which gave a linear calibration curve and large peak-areas of the range corresponding to AsA concentration between 0.2 and 10 μmol/ml. The results indicated that some supports modified with metal-porphine would be applicable to the FIA for AsA as the solid catalyses which function as if the immobilized enzymes.

KW - Ascorbic acid

KW - Catalysis

KW - Flow injection analysis

KW - Metal-porphine

KW - Mimesis of enzyme

KW - Modified carriers

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Flow injection analysis of ascorbic acid using carriers modified with metal-porphine as oxidative solid catalyses

Abstract

Keywords

ASJC Scopus subject areas

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