Abstract
Objectives: The relationships between filtered QRS duration and ventricular dyssynchrony were studied. Methods: We measured filtered QRS duration on signal-averaged electrocardiography and analyzed tissue Doppler imaging in chronic heart failure patients with ejection fraction less than 50%. Results: In 64 patients, interventricular and intraventricular dyssynchronies were observed in 25 and 38 patients, respectively. All patients with interventricular dyssynchrony were associated with intraventricular dyssynchrony. Filtered QRS showed 0.82 and 0.78 of the area under the curve (AUC) in the receiver operating characteristic curve (ROC) for the detection of interventricular and intraventricular dyssynchrony, respectively, with 89.7% and 96.2% specificity and 52.0% and 52.6% sensitivity, with cutoff values of 174 and 153 milliseconds. Specificity and sensitivity as well as AUC were lower in the ROC of QRS duration than filtered QRS duration. Conclusion: Filtered QRS duration provided more reliable information to estimate ventricular dyssynchrony in patients with reduced ventricular ejection fraction than QRS duration did.
| Original language | English |
|---|---|
| Pages (from-to) | 48-53 |
| Number of pages | 6 |
| Journal | Journal of Electrocardiology |
| Volume | 43 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2010 |
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Keywords
- Electrocardiography
- QRS
- Ventricular dyssynchrony
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Filtered QRS duration on signal-averaged electrocardiography correlates with ventricular dyssynchrony assessed by tissue Doppler imaging in patients with reduced ventricular ejection fraction. / Tahara, Tatsuya; Sogou, Taiji; Suezawa, Chisato; Matsubara, Hitoshi; Tada, Norihiro; Tsushima, Sho; Kitawaki, Tomoki; Shinohata, Ryouko; Kusachi, Shozo.
In: Journal of Electrocardiology, Vol. 43, No. 1, 01.2010, p. 48-53.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Filtered QRS duration on signal-averaged electrocardiography correlates with ventricular dyssynchrony assessed by tissue Doppler imaging in patients with reduced ventricular ejection fraction
AU - Tahara, Tatsuya
AU - Sogou, Taiji
AU - Suezawa, Chisato
AU - Matsubara, Hitoshi
AU - Tada, Norihiro
AU - Tsushima, Sho
AU - Kitawaki, Tomoki
AU - Shinohata, Ryouko
AU - Kusachi, Shozo
PY - 2010/1
Y1 - 2010/1
N2 - Objectives: The relationships between filtered QRS duration and ventricular dyssynchrony were studied. Methods: We measured filtered QRS duration on signal-averaged electrocardiography and analyzed tissue Doppler imaging in chronic heart failure patients with ejection fraction less than 50%. Results: In 64 patients, interventricular and intraventricular dyssynchronies were observed in 25 and 38 patients, respectively. All patients with interventricular dyssynchrony were associated with intraventricular dyssynchrony. Filtered QRS showed 0.82 and 0.78 of the area under the curve (AUC) in the receiver operating characteristic curve (ROC) for the detection of interventricular and intraventricular dyssynchrony, respectively, with 89.7% and 96.2% specificity and 52.0% and 52.6% sensitivity, with cutoff values of 174 and 153 milliseconds. Specificity and sensitivity as well as AUC were lower in the ROC of QRS duration than filtered QRS duration. Conclusion: Filtered QRS duration provided more reliable information to estimate ventricular dyssynchrony in patients with reduced ventricular ejection fraction than QRS duration did.
AB - Objectives: The relationships between filtered QRS duration and ventricular dyssynchrony were studied. Methods: We measured filtered QRS duration on signal-averaged electrocardiography and analyzed tissue Doppler imaging in chronic heart failure patients with ejection fraction less than 50%. Results: In 64 patients, interventricular and intraventricular dyssynchronies were observed in 25 and 38 patients, respectively. All patients with interventricular dyssynchrony were associated with intraventricular dyssynchrony. Filtered QRS showed 0.82 and 0.78 of the area under the curve (AUC) in the receiver operating characteristic curve (ROC) for the detection of interventricular and intraventricular dyssynchrony, respectively, with 89.7% and 96.2% specificity and 52.0% and 52.6% sensitivity, with cutoff values of 174 and 153 milliseconds. Specificity and sensitivity as well as AUC were lower in the ROC of QRS duration than filtered QRS duration. Conclusion: Filtered QRS duration provided more reliable information to estimate ventricular dyssynchrony in patients with reduced ventricular ejection fraction than QRS duration did.
KW - Electrocardiography
KW - QRS
KW - Ventricular dyssynchrony
UR - http://www.scopus.com/inward/record.url?scp=71649111833&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=71649111833&partnerID=8YFLogxK
U2 - 10.1016/j.jelectrocard.2009.06.005
DO - 10.1016/j.jelectrocard.2009.06.005
M3 - Article
C2 - 19608196
AN - SCOPUS:71649111833
VL - 43
SP - 48
EP - 53
JO - Journal of Electrocardiology
JF - Journal of Electrocardiology
SN - 0022-0736
IS - 1
ER -