Feasibility, efficacy, and predictive factors for the technical success of endoscopic nasogallbladder drainage: A prospective study

Kei Yane, Hiroyuki Maguchi, Akio Katanuma, Kuniyuki Takahashi, Manabu Osanai, Toshifumi Kin, Ryo Takaki, Kazuyuki Matsumoto, Katsushige Gon, Tomoaki Matsumori, Akiko Tomonari, Masanori Nojima

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background/Aims: Several studies have shown the usefulness of endoscopic nasogallbladder drainage (ENGBD) in patients with acute cholecystitis. However, the procedure is difficult, and factors that affect technical success have not yet been clarified. We conducted a prospective study to evaluate the technical feasibility, efficacy, and predictive factors for the technical success of ENGBD in patients with acute cholecystitis. Methods: All patients with moderate or severe acute cholecystitis who were enrolled underwent ENGBD between April 2009 and April 2011. Patients with surgically altered anatomy or pancreatobiliary malignancies were excluded. The primary outcomes included technical success, clinical success, and complications. Factors that could affect the technical success were also examined. Results: Of the 27 patients who underwent ENGBD during the study period, technical success was achieved in 21 (78%) and clinical improvement was achieved in 20 (95%). Early complications were encountered in four patients (15%). Gallbladder wall thickness (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.08 to 2.47) and age (OR, 1.16; 95% CI, 1.00 to 1.35) were effective predictors of technical failure. Conclusions: ENGBD was effective in resolving acute cholecystitis; however, this modality was technically challenging and had a limited success rate. Because of technical difficulties, ENGBD should be reserved for limited indications.

Original languageEnglish
Pages (from-to)239-246
Number of pages8
JournalGut and liver
Volume9
Issue number2
DOIs
Publication statusPublished - Mar 1 2015
Externally publishedYes

Keywords

  • Acute cholecystitis
  • Endoscopic retrograde cholangiopancreatography
  • Gallbladder drainage

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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    Yane, K., Maguchi, H., Katanuma, A., Takahashi, K., Osanai, M., Kin, T., Takaki, R., Matsumoto, K., Gon, K., Matsumori, T., Tomonari, A., & Nojima, M. (2015). Feasibility, efficacy, and predictive factors for the technical success of endoscopic nasogallbladder drainage: A prospective study. Gut and liver, 9(2), 239-246. https://doi.org/10.5009/gnl14070