Fatal hypothermia related vacuolation of hormone-producing cells in the anterior pituitary

T. Ishikawa, Satoru Miyaishi, T. Tachibana, H. Ishizu, B. L. Zhu, H. Maeda

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34 Citations (Scopus)


We found small cytoplasmic vacuoles in the hormone-producing cells of anterior pituitary in hypothermic death. The vacuoles were found in approximately 40% of anterior pituitary cells both in males and females that had died from cold (n=31) while the detection rate was lower than 1% (P

Original languageEnglish
Pages (from-to)157-163
Number of pages7
JournalLegal Medicine
Issue number3
Publication statusPublished - Jul 2004



  • Cytoplasmic vacuole
  • Electron microscopy
  • Human anterior pituitary
  • Hypothermia
  • Immunohistochemistry

ASJC Scopus subject areas

  • Genetics
  • Pathology and Forensic Medicine
  • Psychiatry and Mental health
  • Public Health, Environmental and Occupational Health

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