Familial pure akinesia

H. Narai, Y. Manabe, T. Murakami, H. Warita, Koji Abe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report a 67-year-old man and his family presenting pure akinesia (PA). He developed bradykinesia. A neurological examination showed a lack of facial expression but no tremor or rigidity. His eye movement was full, and he had frozen gait and pulsion symptoms. There was no evidence of dementia. Levodopa therapy was not effective. Magnetic resonance imaging revealed no brainstem and cerebellar atrophy. 99mTc-ECD-SPECT had no further abnormality. His father and brother had similar symptoms as him. We conclude that this family is the first reported example of pure akinesia with autosomal dominant inheritance.

Original languageEnglish
Pages (from-to)1101-1104
Number of pages4
JournalClinical Neurology
Volume40
Issue number11
Publication statusPublished - 2000

Fingerprint

Hypokinesia
Facial Expression
Neurologic Examination
Levodopa
Tremor
Eye Movements
Single-Photon Emission-Computed Tomography
Gait
Fathers
Brain Stem
Atrophy
Dementia
Siblings
Magnetic Resonance Imaging
Therapeutics
technetium Tc 99m bicisate

Keywords

  • Autosomal dominant inheritance
  • Familial parkinsonism
  • Pure akinesia

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Narai, H., Manabe, Y., Murakami, T., Warita, H., & Abe, K. (2000). Familial pure akinesia. Clinical Neurology, 40(11), 1101-1104.

Familial pure akinesia. / Narai, H.; Manabe, Y.; Murakami, T.; Warita, H.; Abe, Koji.

In: Clinical Neurology, Vol. 40, No. 11, 2000, p. 1101-1104.

Research output: Contribution to journalArticle

Narai, H, Manabe, Y, Murakami, T, Warita, H & Abe, K 2000, 'Familial pure akinesia', Clinical Neurology, vol. 40, no. 11, pp. 1101-1104.
Narai H, Manabe Y, Murakami T, Warita H, Abe K. Familial pure akinesia. Clinical Neurology. 2000;40(11):1101-1104.
Narai, H. ; Manabe, Y. ; Murakami, T. ; Warita, H. ; Abe, Koji. / Familial pure akinesia. In: Clinical Neurology. 2000 ; Vol. 40, No. 11. pp. 1101-1104.
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