Abstract
We describe a 53-year-old woman with chronic interstitial nephritis and asymptomatic impairment of renal function. Seven members of her family were suffering from renal failure and underwent hemodialysis. At the time of their hospital admissions, they had shown evidence of end-stage renal failure at 40 to 50 years of age. Lack of proteinuria, hematuria, hypertension, hyperuricemia, hearing loss, and visual impairment were present before the deterioration of the renal function. Renal biopsy of the presented case indicated chronic interstitial nephritis without glomerular basement membrane abnormalities. Progressive decline of renal function and the inheritance pattern of autosomal dominance in this family suggested the diagnosis of familial interstitial nephritis.
Original language | English |
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Pages (from-to) | E25 |
Journal | American journal of kidney diseases : the official journal of the National Kidney Foundation |
Volume | 36 |
Issue number | 4 |
Publication status | Published - Oct 2000 |
ASJC Scopus subject areas
- Nephrology