Abstract
The past several years have seen an explosive growth in the application of recombinant DNA methods to study the molecular pathology of various inherited disorders. As a consequence, molecular defects responsible for the disease have been identified at the sequence level. In this review, I briefly describe the recent progress in the uses of factor IX gene probes in clinical diagnosis of hemophilia B (Christmas disease) carriers, as well as their use for analyzing the structural gene abnormalities that are responsible for the disease.
| Original language | English |
|---|---|
| Pages (from-to) | 811-815 |
| Number of pages | 5 |
| Journal | Acta Haematologica Japonica |
| Volume | 52 |
| Issue number | 4 |
| Publication status | Published - Jul 1 1989 |
ASJC Scopus subject areas
- Hematology
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Cite this
Tanimoto, M. (1989). Factor IX molecular defects in diagnosing hemophilia B: a review. Acta Haematologica Japonica, 52(4), 811-815.