Factor IX molecular defects in diagnosing hemophilia B: a review.

M. Tanimoto

Research output: Contribution to journalReview articlepeer-review

Abstract

The past several years have seen an explosive growth in the application of recombinant DNA methods to study the molecular pathology of various inherited disorders. As a consequence, molecular defects responsible for the disease have been identified at the sequence level. In this review, I briefly describe the recent progress in the uses of factor IX gene probes in clinical diagnosis of hemophilia B (Christmas disease) carriers, as well as their use for analyzing the structural gene abnormalities that are responsible for the disease.

Original languageEnglish
Pages (from-to)811-815
Number of pages5
JournalActa Haematologica Japonica
Volume52
Issue number4
Publication statusPublished - Jul 1 1989

ASJC Scopus subject areas

  • Hematology

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