Factor IX molecular defects in diagnosing hemophilia B: a review.

M. Tanimoto

Research output: Contribution to journalReview article

Abstract

The past several years have seen an explosive growth in the application of recombinant DNA methods to study the molecular pathology of various inherited disorders. As a consequence, molecular defects responsible for the disease have been identified at the sequence level. In this review, I briefly describe the recent progress in the uses of factor IX gene probes in clinical diagnosis of hemophilia B (Christmas disease) carriers, as well as their use for analyzing the structural gene abnormalities that are responsible for the disease.

Original languageEnglish
Pages (from-to)811-815
Number of pages5
JournalActa Haematologica Japonica
Volume52
Issue number4
Publication statusPublished - Jul 1 1989

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ASJC Scopus subject areas

  • Hematology

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