FAcile synthesis of pyrano[3,2-e]indoles via the basepromoted pictet-spengler reaction of Nb-benzylserotonin

Koji Yamada, Sayaka Yamaguchi, Noriyuki Hatae, Takumi Abe, Tatsunori Iwamura, Minoru Ishikura

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A novel and simple protocol for the synthesis of 1-(2-aminoethyl)- pyrano[3,2-e]indole derivatives has been developed using the Pictet-Spengler reaction of Nb-benzylserotonin with αβ-unsaturated aldehydes in the presence of Et3N in 2-propanol or MeOH.

Original languageEnglish
Pages (from-to)815-826
Number of pages12
JournalHeterocycles
Volume83
Issue number4
DOIs
Publication statusPublished - Mar 28 2011
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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