Abstract
A composite consisting of titanium dioxide (Ti02) particle, the surface of which was modified with amino groups, and a silicone substrate through covalent bonding at their interface was developed, and antibacterial and cell adhesion activities of the composite were evaluated. The density of the amino groups on the Ti02 particle surface was controlled by the reaction time of the modification reaction, and optimized by evaluation of photoreactivity and cell adhesion property of the amino-group-modified TiO 2 particles. The optimum amino group-modified TiO 2/silicone composite sheet (amino group density, 3.0 molecules/nm 2) showed an effective antibacterial activity for E. coli bacteria under UV irradiation, whereas the original silicone sheet showed almost no antibacterial activity under the same UV irradiation conditions.
| Original language | English |
|---|---|
| Title of host publication | Polymer Preprints, Japan |
| Pages | 2000 |
| Number of pages | 1 |
| Volume | 55 |
| Edition | 1 |
| Publication status | Published - 2006 |
| Externally published | Yes |
| Event | 55th SPSJ Annual Meeting - Nagoya, Japan Duration: May 24 2006 → May 26 2006 |
Other
| Other | 55th SPSJ Annual Meeting |
|---|---|
| Country | Japan |
| City | Nagoya |
| Period | 5/24/06 → 5/26/06 |
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Keywords
- Composite
- Medical device
- Photoreactivity
- Tissue adhesion
- Titanium dioxide
ASJC Scopus subject areas
- Engineering(all)
Cite this
Fabrication of medical device from photoreactive particles having tissue-adhesion. / Okada, Masahiro; Masuda, Miwa; Yasuda, Shoji; Furuzono, Tsutomu.
Polymer Preprints, Japan. Vol. 55 1. ed. 2006. p. 2000.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Fabrication of medical device from photoreactive particles having tissue-adhesion
AU - Okada, Masahiro
AU - Masuda, Miwa
AU - Yasuda, Shoji
AU - Furuzono, Tsutomu
PY - 2006
Y1 - 2006
N2 - A composite consisting of titanium dioxide (Ti02) particle, the surface of which was modified with amino groups, and a silicone substrate through covalent bonding at their interface was developed, and antibacterial and cell adhesion activities of the composite were evaluated. The density of the amino groups on the Ti02 particle surface was controlled by the reaction time of the modification reaction, and optimized by evaluation of photoreactivity and cell adhesion property of the amino-group-modified TiO 2 particles. The optimum amino group-modified TiO 2/silicone composite sheet (amino group density, 3.0 molecules/nm 2) showed an effective antibacterial activity for E. coli bacteria under UV irradiation, whereas the original silicone sheet showed almost no antibacterial activity under the same UV irradiation conditions.
AB - A composite consisting of titanium dioxide (Ti02) particle, the surface of which was modified with amino groups, and a silicone substrate through covalent bonding at their interface was developed, and antibacterial and cell adhesion activities of the composite were evaluated. The density of the amino groups on the Ti02 particle surface was controlled by the reaction time of the modification reaction, and optimized by evaluation of photoreactivity and cell adhesion property of the amino-group-modified TiO 2 particles. The optimum amino group-modified TiO 2/silicone composite sheet (amino group density, 3.0 molecules/nm 2) showed an effective antibacterial activity for E. coli bacteria under UV irradiation, whereas the original silicone sheet showed almost no antibacterial activity under the same UV irradiation conditions.
KW - Composite
KW - Medical device
KW - Photoreactivity
KW - Tissue adhesion
KW - Titanium dioxide
UR - http://www.scopus.com/inward/record.url?scp=33749851554&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749851554&partnerID=8YFLogxK
M3 - Conference contribution
VL - 55
SP - 2000
BT - Polymer Preprints, Japan
ER -