Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions

Yuko Omori, Masahiro Okada, Shoji Takeda, Naoyuki Matsumoto

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Various techniques for preparing ceramic nanoparticles have been developed; however, most of them start from a preparation of precursor nanoparticles that are generally amorphous or in poorly crystallized phases. Thermal treatments used to obtain crystalline phases typically result in the sintering of the products into large polycrystals. In this study, we developed a process to fabricate dispersible hydroxyapatite (HAp; Ca10(PO4) 6(OH)2) nanocrystals via a modified Pechini method, which is a sol-gel like solid-state synthesis method for the preparation of multicomponent oxides. We demonstrated that the HAp nanocrystals sintered into large polycrystals ranging in size from several tens to several hundreds of microns via a conventional Pechini method using the stoichiometric Ca/P molar ratio of 1.67. When the Ca/P molar ratio in the precursor was > 1.67, a mixture of HAp nanocrystals and removable CaO matrix was obtained. The HAp nanocrystals were dispersed in aqueous media mostly in the form of nanoparticles when the amount of CaO matrix was sufficiently greater than the amount of HAp.

Original languageEnglish
Pages (from-to)562-568
Number of pages7
JournalMaterials Science and Engineering C
Volume42
DOIs
Publication statusPublished - Sep 1 2014
Externally publishedYes

Fingerprint

calcium phosphates
Calcium phosphate
Nanoparticles
Nanocrystals
nanocrystals
Fabrication
fabrication
Polycrystals
polycrystals
nanoparticles
preparation
Durapatite
matrices
Hydroxyapatite
Oxides
Sol-gels
sintering
Sintering
Heat treatment
gels

Keywords

  • Calcium phosphate
  • Dispersible
  • Nanocrystal
  • Nanoparticle
  • Pechini method

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering
  • Mechanics of Materials
  • Medicine(all)

Cite this

Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions. / Omori, Yuko; Okada, Masahiro; Takeda, Shoji; Matsumoto, Naoyuki.

In: Materials Science and Engineering C, Vol. 42, 01.09.2014, p. 562-568.

Research output: Contribution to journalArticle

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