Abstract
Various techniques for preparing ceramic nanoparticles have been developed; however, most of them start from a preparation of precursor nanoparticles that are generally amorphous or in poorly crystallized phases. Thermal treatments used to obtain crystalline phases typically result in the sintering of the products into large polycrystals. In this study, we developed a process to fabricate dispersible hydroxyapatite (HAp; Ca10(PO4) 6(OH)2) nanocrystals via a modified Pechini method, which is a sol-gel like solid-state synthesis method for the preparation of multicomponent oxides. We demonstrated that the HAp nanocrystals sintered into large polycrystals ranging in size from several tens to several hundreds of microns via a conventional Pechini method using the stoichiometric Ca/P molar ratio of 1.67. When the Ca/P molar ratio in the precursor was > 1.67, a mixture of HAp nanocrystals and removable CaO matrix was obtained. The HAp nanocrystals were dispersed in aqueous media mostly in the form of nanoparticles when the amount of CaO matrix was sufficiently greater than the amount of HAp.
| Original language | English |
|---|---|
| Pages (from-to) | 562-568 |
| Number of pages | 7 |
| Journal | Materials Science and Engineering C |
| Volume | 42 |
| DOIs | |
| Publication status | Published - Sep 1 2014 |
| Externally published | Yes |
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Keywords
- Calcium phosphate
- Dispersible
- Nanocrystal
- Nanoparticle
- Pechini method
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanical Engineering
- Mechanics of Materials
- Medicine(all)
Cite this
Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions. / Omori, Yuko; Okada, Masahiro; Takeda, Shoji; Matsumoto, Naoyuki.
In: Materials Science and Engineering C, Vol. 42, 01.09.2014, p. 562-568.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions
AU - Omori, Yuko
AU - Okada, Masahiro
AU - Takeda, Shoji
AU - Matsumoto, Naoyuki
PY - 2014/9/1
Y1 - 2014/9/1
N2 - Various techniques for preparing ceramic nanoparticles have been developed; however, most of them start from a preparation of precursor nanoparticles that are generally amorphous or in poorly crystallized phases. Thermal treatments used to obtain crystalline phases typically result in the sintering of the products into large polycrystals. In this study, we developed a process to fabricate dispersible hydroxyapatite (HAp; Ca10(PO4) 6(OH)2) nanocrystals via a modified Pechini method, which is a sol-gel like solid-state synthesis method for the preparation of multicomponent oxides. We demonstrated that the HAp nanocrystals sintered into large polycrystals ranging in size from several tens to several hundreds of microns via a conventional Pechini method using the stoichiometric Ca/P molar ratio of 1.67. When the Ca/P molar ratio in the precursor was > 1.67, a mixture of HAp nanocrystals and removable CaO matrix was obtained. The HAp nanocrystals were dispersed in aqueous media mostly in the form of nanoparticles when the amount of CaO matrix was sufficiently greater than the amount of HAp.
AB - Various techniques for preparing ceramic nanoparticles have been developed; however, most of them start from a preparation of precursor nanoparticles that are generally amorphous or in poorly crystallized phases. Thermal treatments used to obtain crystalline phases typically result in the sintering of the products into large polycrystals. In this study, we developed a process to fabricate dispersible hydroxyapatite (HAp; Ca10(PO4) 6(OH)2) nanocrystals via a modified Pechini method, which is a sol-gel like solid-state synthesis method for the preparation of multicomponent oxides. We demonstrated that the HAp nanocrystals sintered into large polycrystals ranging in size from several tens to several hundreds of microns via a conventional Pechini method using the stoichiometric Ca/P molar ratio of 1.67. When the Ca/P molar ratio in the precursor was > 1.67, a mixture of HAp nanocrystals and removable CaO matrix was obtained. The HAp nanocrystals were dispersed in aqueous media mostly in the form of nanoparticles when the amount of CaO matrix was sufficiently greater than the amount of HAp.
KW - Calcium phosphate
KW - Dispersible
KW - Nanocrystal
KW - Nanoparticle
KW - Pechini method
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U2 - 10.1016/j.msec.2014.05.071
DO - 10.1016/j.msec.2014.05.071
M3 - Article
VL - 42
SP - 562
EP - 568
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
SN - 0928-4931
ER -