TY - GEN
T1 - Fabrication of chelate-setting cement using silicon-substituted hydroxyapatite and its property
AU - Nakashima, Y.
AU - Honda, M.
AU - Konishi, T.
AU - Mizumoto, M.
AU - Aizawa, M.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2012
Y1 - 2012
N2 - We have developed novel hydroxyapatite (HAp) cement, "chelate-setting HAp cement" on the basis of chelate bonding of inositol hexaphosphate (IP6). In order to create the cement with enhanced bioactivity, we used a silicon-substituted hydroxyapatite (Si-HAp) as a starting material instead of pure HAp powder. The Si-HAp powders were prepared via an aqueous precipitation reaction and surface-modified with IP6 (IP6-Si-HAp). The Si-HAp were synthesized with desired Si contents (0, 0.4, 0.8, 1.6, and 2.4 mass%). Regardless of the amount of Si, the XRD patterns and FT-IR spectra of the powders were similar to each other. Additionally, chemical composition of Si-HAp powders were the almost same as the nominal one. The substitution of Si resulted in a decrease in the a-axis and increase in the c-axis of unit cell of HAp. While, the compressive strength of IP6-Si-HAp cements was higher than that of Si-HAp cements. These results suggest that surface-modification of any powders with IP6 is effective for enhancement of mechanical property. Comparison of mechanical property between HAp and Si-HAp cement specimens revealed that the substitution of lower levels of Si into0 HAp lattice did not greatly influence compressive strength. However, the substitution of high dose of Si (over 2.4 mass%) reduced the compressive strength. Therefore, to fabricate the chelate-setting cements with enhanced bioactivity, it is necessary to control the amount of Si.
AB - We have developed novel hydroxyapatite (HAp) cement, "chelate-setting HAp cement" on the basis of chelate bonding of inositol hexaphosphate (IP6). In order to create the cement with enhanced bioactivity, we used a silicon-substituted hydroxyapatite (Si-HAp) as a starting material instead of pure HAp powder. The Si-HAp powders were prepared via an aqueous precipitation reaction and surface-modified with IP6 (IP6-Si-HAp). The Si-HAp were synthesized with desired Si contents (0, 0.4, 0.8, 1.6, and 2.4 mass%). Regardless of the amount of Si, the XRD patterns and FT-IR spectra of the powders were similar to each other. Additionally, chemical composition of Si-HAp powders were the almost same as the nominal one. The substitution of Si resulted in a decrease in the a-axis and increase in the c-axis of unit cell of HAp. While, the compressive strength of IP6-Si-HAp cements was higher than that of Si-HAp cements. These results suggest that surface-modification of any powders with IP6 is effective for enhancement of mechanical property. Comparison of mechanical property between HAp and Si-HAp cement specimens revealed that the substitution of lower levels of Si into0 HAp lattice did not greatly influence compressive strength. However, the substitution of high dose of Si (over 2.4 mass%) reduced the compressive strength. Therefore, to fabricate the chelate-setting cements with enhanced bioactivity, it is necessary to control the amount of Si.
KW - Cement
KW - Hydroxyapatite
KW - Inositol phosphate
KW - Silicon-substituted hydroxyapatite
UR - http://www.scopus.com/inward/record.url?scp=81555211926&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=81555211926&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.493-494.370
DO - 10.4028/www.scientific.net/KEM.493-494.370
M3 - Conference contribution
AN - SCOPUS:81555211926
SN - 9783037852552
T3 - Key Engineering Materials
SP - 370
EP - 374
BT - Bioceramics 23
PB - Trans Tech Publications Ltd
T2 - 23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011
Y2 - 6 November 2011 through 9 November 2011
ER -