Abstract
We have developed novel hydroxyapatite (HAp) cement, "chelate-setting HAp cement" on the basis of chelate bonding of inositol hexaphosphate (IP6). In order to create the cement with enhanced bioactivity, we used a silicon-substituted hydroxyapatite (Si-HAp) as a starting material instead of pure HAp powder. The Si-HAp powders were prepared via an aqueous precipitation reaction and surface-modified with IP6 (IP6-Si-HAp). The Si-HAp were synthesized with desired Si contents (0, 0.4, 0.8, 1.6, and 2.4 mass%). Regardless of the amount of Si, the XRD patterns and FT-IR spectra of the powders were similar to each other. Additionally, chemical composition of Si-HAp powders were the almost same as the nominal one. The substitution of Si resulted in a decrease in the a-axis and increase in the c-axis of unit cell of HAp. While, the compressive strength of IP6-Si-HAp cements was higher than that of Si-HAp cements. These results suggest that surface-modification of any powders with IP6 is effective for enhancement of mechanical property. Comparison of mechanical property between HAp and Si-HAp cement specimens revealed that the substitution of lower levels of Si into0 HAp lattice did not greatly influence compressive strength. However, the substitution of high dose of Si (over 2.4 mass%) reduced the compressive strength. Therefore, to fabricate the chelate-setting cements with enhanced bioactivity, it is necessary to control the amount of Si.
| Original language | English |
|---|---|
| Title of host publication | Key Engineering Materials |
| Pages | 370-374 |
| Number of pages | 5 |
| Volume | 493-494 |
| DOIs | |
| Publication status | Published - 2012 |
| Externally published | Yes |
| Event | 23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011 - Istanbul, Turkey Duration: Nov 6 2011 → Nov 9 2011 |
Publication series
| Name | Key Engineering Materials |
|---|---|
| Volume | 493-494 |
| ISSN (Print) | 10139826 |
Other
| Other | 23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011 |
|---|---|
| Country | Turkey |
| City | Istanbul |
| Period | 11/6/11 → 11/9/11 |
Fingerprint
Keywords
- Cement
- Hydroxyapatite
- Inositol phosphate
- Silicon-substituted hydroxyapatite
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering
Cite this
Fabrication of chelate-setting cement using silicon-substituted hydroxyapatite and its property. / Nakashima, Y.; Honda, M.; Konishi, T.; Mizumoto, M.; Aizawa, M.
Key Engineering Materials. Vol. 493-494 2012. p. 370-374 (Key Engineering Materials; Vol. 493-494).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Fabrication of chelate-setting cement using silicon-substituted hydroxyapatite and its property
AU - Nakashima, Y.
AU - Honda, M.
AU - Konishi, T.
AU - Mizumoto, M.
AU - Aizawa, M.
PY - 2012
Y1 - 2012
N2 - We have developed novel hydroxyapatite (HAp) cement, "chelate-setting HAp cement" on the basis of chelate bonding of inositol hexaphosphate (IP6). In order to create the cement with enhanced bioactivity, we used a silicon-substituted hydroxyapatite (Si-HAp) as a starting material instead of pure HAp powder. The Si-HAp powders were prepared via an aqueous precipitation reaction and surface-modified with IP6 (IP6-Si-HAp). The Si-HAp were synthesized with desired Si contents (0, 0.4, 0.8, 1.6, and 2.4 mass%). Regardless of the amount of Si, the XRD patterns and FT-IR spectra of the powders were similar to each other. Additionally, chemical composition of Si-HAp powders were the almost same as the nominal one. The substitution of Si resulted in a decrease in the a-axis and increase in the c-axis of unit cell of HAp. While, the compressive strength of IP6-Si-HAp cements was higher than that of Si-HAp cements. These results suggest that surface-modification of any powders with IP6 is effective for enhancement of mechanical property. Comparison of mechanical property between HAp and Si-HAp cement specimens revealed that the substitution of lower levels of Si into0 HAp lattice did not greatly influence compressive strength. However, the substitution of high dose of Si (over 2.4 mass%) reduced the compressive strength. Therefore, to fabricate the chelate-setting cements with enhanced bioactivity, it is necessary to control the amount of Si.
AB - We have developed novel hydroxyapatite (HAp) cement, "chelate-setting HAp cement" on the basis of chelate bonding of inositol hexaphosphate (IP6). In order to create the cement with enhanced bioactivity, we used a silicon-substituted hydroxyapatite (Si-HAp) as a starting material instead of pure HAp powder. The Si-HAp powders were prepared via an aqueous precipitation reaction and surface-modified with IP6 (IP6-Si-HAp). The Si-HAp were synthesized with desired Si contents (0, 0.4, 0.8, 1.6, and 2.4 mass%). Regardless of the amount of Si, the XRD patterns and FT-IR spectra of the powders were similar to each other. Additionally, chemical composition of Si-HAp powders were the almost same as the nominal one. The substitution of Si resulted in a decrease in the a-axis and increase in the c-axis of unit cell of HAp. While, the compressive strength of IP6-Si-HAp cements was higher than that of Si-HAp cements. These results suggest that surface-modification of any powders with IP6 is effective for enhancement of mechanical property. Comparison of mechanical property between HAp and Si-HAp cement specimens revealed that the substitution of lower levels of Si into0 HAp lattice did not greatly influence compressive strength. However, the substitution of high dose of Si (over 2.4 mass%) reduced the compressive strength. Therefore, to fabricate the chelate-setting cements with enhanced bioactivity, it is necessary to control the amount of Si.
KW - Cement
KW - Hydroxyapatite
KW - Inositol phosphate
KW - Silicon-substituted hydroxyapatite
UR - http://www.scopus.com/inward/record.url?scp=81555211926&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=81555211926&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.493-494.370
DO - 10.4028/www.scientific.net/KEM.493-494.370
M3 - Conference contribution
AN - SCOPUS:81555211926
SN - 9783037852552
VL - 493-494
T3 - Key Engineering Materials
SP - 370
EP - 374
BT - Key Engineering Materials
ER -