Extramedullary plasmacytoma

Cytological and genotypic studies

T. Tamamori, F. Nakayama, H. Sugimoto, J. Fenxiang, K. Iwatsuki, M. Takigawa

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A 62-year-old woman had multiple plasmacytomas in the skin and lymph nodes, without Bence-Jones protein or a monoclonal peak of serum immunoglobulins. Infiltrating plasmacytoid cells expressed cytoplasmic IgG (λ) and surface CD38, without any B-cell markers. There was no visceral or bone marrow involvement suggestive of multiple myeloma. Southern blot analysis of extracted DNA from the cutaneous lesions showed two rearranged bands with an immunoglobulin, but not a T-cell receptor, gene probe. The patient showed a poor response to chemotherapy, and died of The clinical course and cytological features differentiate multiple cutaneous extramedullary plasmacytomas from solitary cutaneous extramedullary plasmacytoma and cutaneous lesions associated with multiple myeloma.

Original languageEnglish
Pages (from-to)468-472
Number of pages5
JournalBritish Journal of Dermatology
Volume129
Issue number4
DOIs
Publication statusPublished - 1993
Externally publishedYes

Fingerprint

Plasmacytoma
Skin
Multiple Myeloma
Immunoglobulins
Bence Jones Protein
T-Cell Receptor Genes
Southern Blotting
B-Lymphocytes
Immunoglobulin G
Lymph Nodes
Bone Marrow
Drug Therapy
DNA
Serum

ASJC Scopus subject areas

  • Dermatology

Cite this

Tamamori, T., Nakayama, F., Sugimoto, H., Fenxiang, J., Iwatsuki, K., & Takigawa, M. (1993). Extramedullary plasmacytoma: Cytological and genotypic studies. British Journal of Dermatology, 129(4), 468-472. https://doi.org/10.1111/j.1365-2133.1993.tb03180.x

Extramedullary plasmacytoma : Cytological and genotypic studies. / Tamamori, T.; Nakayama, F.; Sugimoto, H.; Fenxiang, J.; Iwatsuki, K.; Takigawa, M.

In: British Journal of Dermatology, Vol. 129, No. 4, 1993, p. 468-472.

Research output: Contribution to journalArticle

Tamamori, T, Nakayama, F, Sugimoto, H, Fenxiang, J, Iwatsuki, K & Takigawa, M 1993, 'Extramedullary plasmacytoma: Cytological and genotypic studies', British Journal of Dermatology, vol. 129, no. 4, pp. 468-472. https://doi.org/10.1111/j.1365-2133.1993.tb03180.x
Tamamori T, Nakayama F, Sugimoto H, Fenxiang J, Iwatsuki K, Takigawa M. Extramedullary plasmacytoma: Cytological and genotypic studies. British Journal of Dermatology. 1993;129(4):468-472. https://doi.org/10.1111/j.1365-2133.1993.tb03180.x
Tamamori, T. ; Nakayama, F. ; Sugimoto, H. ; Fenxiang, J. ; Iwatsuki, K. ; Takigawa, M. / Extramedullary plasmacytoma : Cytological and genotypic studies. In: British Journal of Dermatology. 1993 ; Vol. 129, No. 4. pp. 468-472.
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