Abstract
Vibrio cholerae is an aerobic, sucrose fermentative Gram-negative bacterium that generally prevails in the environment. Pathogenic V. cholerae is well-known as causative agent of acute diarrhea. Apart from enteric infections, V. cholerae may also cause other diseases. However, their role in causing extraintestinal infections is not fully known as it needs proper identification and evaluation. Four cases of extraintestinal infections due to V. cholerae non-O1/non-O139 have been investigated. The isolates were screened for phenotypic and genetic characteristics with reference to their major virulence genes. Serologically distinct isolates harbored rtx, msh, and hly but lacked enteric toxin encoding genes that are generally present in toxigenic V. cholerae. Timely detection of this organism can prevent fatalities in hospital settings. The underlying virulence potential of V. cholerae needs appropriate testing and intervention.
| Original language | English |
|---|---|
| Article number | 144 |
| Journal | Frontiers in Microbiology |
| Volume | 7 |
| Issue number | FEB |
| DOIs | |
| Publication status | Published - Feb 11 2016 |
| Externally published | Yes |
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Keywords
- Hematuria
- OmpW-PCR
- Septicaemia
- Serogroup identification
- UTI
- V. cholerae
ASJC Scopus subject areas
- Microbiology
- Microbiology (medical)
Cite this
Extraintestinal infections caused by non-toxigenic Vibrio cholerae non-O1/non-O139. / Chowdhury, Goutam; Joshi, Sangeeta; Bhattacharya, Sanjay; Sekar, Uma; Birajdar, Balaji; Bhattacharyya, Arpita; Shinoda, Sumio; Ramamurthy, Thandavarayan.
In: Frontiers in Microbiology, Vol. 7, No. FEB, 144, 11.02.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Extraintestinal infections caused by non-toxigenic Vibrio cholerae non-O1/non-O139
AU - Chowdhury, Goutam
AU - Joshi, Sangeeta
AU - Bhattacharya, Sanjay
AU - Sekar, Uma
AU - Birajdar, Balaji
AU - Bhattacharyya, Arpita
AU - Shinoda, Sumio
AU - Ramamurthy, Thandavarayan
PY - 2016/2/11
Y1 - 2016/2/11
N2 - Vibrio cholerae is an aerobic, sucrose fermentative Gram-negative bacterium that generally prevails in the environment. Pathogenic V. cholerae is well-known as causative agent of acute diarrhea. Apart from enteric infections, V. cholerae may also cause other diseases. However, their role in causing extraintestinal infections is not fully known as it needs proper identification and evaluation. Four cases of extraintestinal infections due to V. cholerae non-O1/non-O139 have been investigated. The isolates were screened for phenotypic and genetic characteristics with reference to their major virulence genes. Serologically distinct isolates harbored rtx, msh, and hly but lacked enteric toxin encoding genes that are generally present in toxigenic V. cholerae. Timely detection of this organism can prevent fatalities in hospital settings. The underlying virulence potential of V. cholerae needs appropriate testing and intervention.
AB - Vibrio cholerae is an aerobic, sucrose fermentative Gram-negative bacterium that generally prevails in the environment. Pathogenic V. cholerae is well-known as causative agent of acute diarrhea. Apart from enteric infections, V. cholerae may also cause other diseases. However, their role in causing extraintestinal infections is not fully known as it needs proper identification and evaluation. Four cases of extraintestinal infections due to V. cholerae non-O1/non-O139 have been investigated. The isolates were screened for phenotypic and genetic characteristics with reference to their major virulence genes. Serologically distinct isolates harbored rtx, msh, and hly but lacked enteric toxin encoding genes that are generally present in toxigenic V. cholerae. Timely detection of this organism can prevent fatalities in hospital settings. The underlying virulence potential of V. cholerae needs appropriate testing and intervention.
KW - Hematuria
KW - OmpW-PCR
KW - Septicaemia
KW - Serogroup identification
KW - UTI
KW - V. cholerae
UR - http://www.scopus.com/inward/record.url?scp=84962140622&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84962140622&partnerID=8YFLogxK
U2 - 10.3389/fmicb.2016.00144
DO - 10.3389/fmicb.2016.00144
M3 - Article
AN - SCOPUS:84962140622
VL - 7
JO - Frontiers in Microbiology
JF - Frontiers in Microbiology
SN - 1664-302X
IS - FEB
M1 - 144
ER -