Extradural temporopolar approach for giant pituitary adenomas invading the cavernous sinus and parasellar regions

Takashi Tamiya, Yasuhiro Ono, Isao Date, Masamitsu Kawauchi, Kengo Matsumoto, Takashi Ohmoto

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: An extradural temporopolar approach has recently been used in the treatment of the parasellar, infrachiasmatic, or intracavernous regions. In this approach, the temporal (superficial) dural layer is separated from the deep layer (inner cavernous membrane) to expose the cavernous sinus extradurally. We report our experiences with 5 cases in which a giant pituitary adenoma invading the cavernous sinus and parasellar regions was resected via the extradural temporopolar approach. Patients and Methods: Between January 1995 and December 1997, 60 patients with pituitary adenomas were operated on at Okayama University Hospital. The extradural temporopolar approach was used for 5 patients who had a giant pituitary adenoma invading the cavernous sinus and parasellar regions. The 5 patients were women aged from 32 to 62 years and presented with a visual dysfunction. Four patients had hormonally non-functioning pituitary adenomas and one had a growth- hormone secreting pituitary adenoma. Results: The operations resulted in 1 total, 3 subtotal and 1 partial removal. There was no operative mortality or major morbidity. Transient oculomotor palsy occurred in 2 cases postoperatively. This approach provided excellent exposure of the tumor, relevant cranial nerves and arteries in and around the cavernous sinus through extradural retraction of the temporal lobe, allowing for sufficient resection of the intracavernous and parasellar portion of the tumor. Tumors invading the inferior portion of the clivus or the contralateral cavernous sinus could not be removed through this approach. Conclusion: Our findings suggest that the extradural temporopolar approach is useful for resection of giant pituitary adenomas invading the cavernous sinus and parasellar regions.

Original languageEnglish
Pages (from-to)803-811
Number of pages9
JournalNeurological Surgery
Volume26
Issue number9
Publication statusPublished - Sep 1 1998

Keywords

  • Cavernous sinus
  • Extradural temporopolar approach
  • Parasellar region
  • Pituitary adenoma
  • Skull base tumors

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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