Expression profiles of genes encoded by the supernumerary chromosome controlling AM-toxin biosynthesis and pathogenicity in the apple pathotype of Alternaria alternata

Yoshiaki Harimoto, Rieko Hatta, Motoichiro Kodama, Mikihiro Yamamoto, Hiroshi Otani, Takashi Tsuge

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The apple pathotype of Alternaria alternata produces host-specific AM-toxin and causes Alternaria blotch of apple. Previously, we cloned two genes, AMT1 and AMT2, required for AM-toxin biosynthesis and found that these genes are encoded by small, supernumerary chromosomes of 10-fold) in AM-toxin-producing cultures. Two of the upregulated genes were newly identified to be involved in AM-toxin biosynthesis by the gene disruption experiments and were named AMT3 and AMT4. Thus, the genes upregulated in AM-toxin-producing cultures contain ideal candidates for novel AM-toxin biosynthetic genes.

Original languageEnglish
Pages (from-to)1463-1476
Number of pages14
JournalMolecular Plant-Microbe Interactions
Volume20
Issue number12
DOIs
Publication statusPublished - Dec 2007

Fingerprint

Alternaria
Alternaria alternata
Biosynthesis
pathotypes
Malus
Chromosomes
Transcriptome
Virulence
toxins
pathogenicity
apples
Genes
biosynthesis
genes
Cell culture
Chromosomes, Human, Pair 10
gene targeting
B chromosomes

Keywords

  • Host-specific toxin

ASJC Scopus subject areas

  • Microbiology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biotechnology

Cite this

Expression profiles of genes encoded by the supernumerary chromosome controlling AM-toxin biosynthesis and pathogenicity in the apple pathotype of Alternaria alternata. / Harimoto, Yoshiaki; Hatta, Rieko; Kodama, Motoichiro; Yamamoto, Mikihiro; Otani, Hiroshi; Tsuge, Takashi.

In: Molecular Plant-Microbe Interactions, Vol. 20, No. 12, 12.2007, p. 1463-1476.

Research output: Contribution to journalArticle

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