Expression of vascular endothelial growth factor-C predicts regional lymph node metastasis in early oral squamous cell carcinoma

Koji Kishimoto, Akira Sasaki, Yasuto Yoshihama, Hiroshi Mese, Goichi Tsukamoto, Tomohiro Matsumura

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

The purpose of this study was to investigate the association of the expression of vascular endothelial growth factor-C (VEGF-C) with regional lymph node metastasis in oral squamous cell carcinoma (OSCC). The expression of VEGF-C in biopsy specimens obtained from 62 patients with OSCC was examined by immunohistochemistry. In the early stages of T1 and T2 (38 cases), VEGF-C expression strongly correlated with lymph node metastasis (P

Original languageEnglish
Pages (from-to)391-396
Number of pages6
JournalOral Oncology
Volume39
Issue number4
DOIs
Publication statusPublished - Jun 2003

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Vascular Endothelial Growth Factor C
Squamous Cell Carcinoma
Lymph Nodes
Neoplasm Metastasis
Immunohistochemistry
Biopsy

Keywords

  • Oral squamous cell carcinoma
  • Regional lymph node metastasis
  • VEGF-C

ASJC Scopus subject areas

  • Oncology

Cite this

Expression of vascular endothelial growth factor-C predicts regional lymph node metastasis in early oral squamous cell carcinoma. / Kishimoto, Koji; Sasaki, Akira; Yoshihama, Yasuto; Mese, Hiroshi; Tsukamoto, Goichi; Matsumura, Tomohiro.

In: Oral Oncology, Vol. 39, No. 4, 06.2003, p. 391-396.

Research output: Contribution to journalArticle

Kishimoto, Koji ; Sasaki, Akira ; Yoshihama, Yasuto ; Mese, Hiroshi ; Tsukamoto, Goichi ; Matsumura, Tomohiro. / Expression of vascular endothelial growth factor-C predicts regional lymph node metastasis in early oral squamous cell carcinoma. In: Oral Oncology. 2003 ; Vol. 39, No. 4. pp. 391-396.
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