Abstract
On the basis of the cellular morphological changes in the cartilaginous area, the mandibular condylar cartilage is histopathologically composed of four different cell layers - fibrous, proliferative, maturative, and hypertrophic. Reaction for Notch1 was present in the hypertrophic cells only. However, Math1 was locally distributed in the hypertrophic layer and partially in the proliferative layer. The expression patterns of Notch1 and Math1 were slightly different. These results suggest that the morphogenesis regulation factors of Notch1 and Math1 may play some role in mandibular condylar cartilage. Positive reactions to osteopontin, as a control, were detected in the cytoplasm of all layers, although they varied from published data.
| Original language | English |
|---|---|
| Pages (from-to) | 993-995 |
| Number of pages | 3 |
| Journal | Angle Orthodontist |
| Volume | 75 |
| Issue number | 6 |
| Publication status | Published - Nov 2005 |
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Keywords
- Immunohistochemistry
- Mandibular condylar cartilage
- Math1
- Notch1
- Osteopontin
ASJC Scopus subject areas
- Dentistry(all)
Cite this
Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice. / Shimizu, Takako; Tsujigiwa, Hidetsugu; Nagatsuka, Hitoshi; Okafuji, Norimasa; Kurihara, Saburo; Nagai, Noriyuki; Kawakami, Toshiyuki.
In: Angle Orthodontist, Vol. 75, No. 6, 11.2005, p. 993-995.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice
AU - Shimizu, Takako
AU - Tsujigiwa, Hidetsugu
AU - Nagatsuka, Hitoshi
AU - Okafuji, Norimasa
AU - Kurihara, Saburo
AU - Nagai, Noriyuki
AU - Kawakami, Toshiyuki
PY - 2005/11
Y1 - 2005/11
N2 - On the basis of the cellular morphological changes in the cartilaginous area, the mandibular condylar cartilage is histopathologically composed of four different cell layers - fibrous, proliferative, maturative, and hypertrophic. Reaction for Notch1 was present in the hypertrophic cells only. However, Math1 was locally distributed in the hypertrophic layer and partially in the proliferative layer. The expression patterns of Notch1 and Math1 were slightly different. These results suggest that the morphogenesis regulation factors of Notch1 and Math1 may play some role in mandibular condylar cartilage. Positive reactions to osteopontin, as a control, were detected in the cytoplasm of all layers, although they varied from published data.
AB - On the basis of the cellular morphological changes in the cartilaginous area, the mandibular condylar cartilage is histopathologically composed of four different cell layers - fibrous, proliferative, maturative, and hypertrophic. Reaction for Notch1 was present in the hypertrophic cells only. However, Math1 was locally distributed in the hypertrophic layer and partially in the proliferative layer. The expression patterns of Notch1 and Math1 were slightly different. These results suggest that the morphogenesis regulation factors of Notch1 and Math1 may play some role in mandibular condylar cartilage. Positive reactions to osteopontin, as a control, were detected in the cytoplasm of all layers, although they varied from published data.
KW - Immunohistochemistry
KW - Mandibular condylar cartilage
KW - Math1
KW - Notch1
KW - Osteopontin
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UR - http://www.scopus.com/inward/citedby.url?scp=29444448358&partnerID=8YFLogxK
M3 - Article
C2 - 16448243
AN - SCOPUS:29444448358
VL - 75
SP - 993
EP - 995
JO - Angle Orthodontist
JF - Angle Orthodontist
SN - 0003-3219
IS - 6
ER -