Expression of HSP in dental root pulp cells due to experimental orthodontic mechanical stress

Keisuke Nakano, Rina Muraoka, Mihoko Tomida, Sachiko Matsuura, Norimasa Okafuji, Chong Huat Siar, Toshiyuki Kawakami

Research output: Contribution to journalArticle

5 Citations (Scopus)


Using immunohistochemical techniques, we examined the expression of heat shock protein (HSP) appearing in murine dental pulp cells after the application of experimental orthodontic mechanical stress. We used Waldo's method, and the results demonstrate that the dental root pulp cells expressed HSP in a comparatively short time after stress. The results suggest that HSP works as one of the mechanisms to maintain homeostasis.

Original languageEnglish
Pages (from-to)127-130
Number of pages4
JournalJournal of Hard Tissue Biology
Issue number3
Publication statusPublished - 2009
Externally publishedYes



  • Dental pulp cells
  • Heat shock protein (HSP)
  • Mechanical stress
  • Odontoblasts
  • Orthodontics

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Biomaterials
  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Dentistry(all)

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