TY - JOUR
T1 - Expressed emotion of families and the course of mood disorders
T2 - A cohort study in Japan
AU - Mino, Yoshio
AU - Shimodera, Shinji
AU - Inoue, Shimpei
AU - Fujita, Hirokazu
AU - Tanaka, Shuichi
AU - Kanazawa, Susumu
N1 - Funding Information:
The authors express their thanks to the patients and their families who kindly participated in this study, to Dr. Koichiro Sudo, Tosa Hospital, and Professor Shozo Aoki, Department of Psychiatry, Kawasaki Medical School, for their assistance and discussion. This study was partly funded by a 1996 subsidy by the Uehara Memorial Foundation and a 1998–2000 grant-in-aid for scientific research (B) from the Japan Ministry of Education, Science, Sports and Culture (grant No. 10470108).
PY - 2001
Y1 - 2001
N2 - Background: Findings on expressed emotion (EE) of the family and the course of mood disorders have not been consistent. There has also been no report on these problems from Asia. Methods: The subjects were 32 patients diagnosed to have mood disorders on the basis of DSM-IV and ICD-10 and 36 principal members of their families. EE was evaluated using Camberwell Family Interview (CFI). A cohort study was conducted for 9 months after discharge of the patients. The patients were divided into a high-EE group and a low-EE group using a few cut-off points concerning the number of critical comments (CCs) and emotional over-involvement (EOI), the 9-month relapse risks were compared, and the relapse risk ratio and its 95% confidence interval were calculated. Also, the sensitivity, specificity, positive predictive value, and negative predictive value were calculated, and the optimal cut-off point was evaluated. Multiple logistic regression analysis was performed to control the effects of potential confounding factors. Results: When the subjects with three or more CCs, or an EOI score of three or higher were regarded as a high-EE group, and the others as a low-EE group, the nine-month relapse risks were 83.3% (5/6) and 19.2% (5/26), respectively, and the relapse risk ratio (95% confidence interval) was 4.3 (1.8-12.2). The values of the validity parameters were the highest with these cut-off points. The effect of EE was also significant on multiple logistic regression analysis. Limitations: Small sample size and severity of the patients. Conclusions: Families' EE based on CFI correlated with relapse also in Japan.
AB - Background: Findings on expressed emotion (EE) of the family and the course of mood disorders have not been consistent. There has also been no report on these problems from Asia. Methods: The subjects were 32 patients diagnosed to have mood disorders on the basis of DSM-IV and ICD-10 and 36 principal members of their families. EE was evaluated using Camberwell Family Interview (CFI). A cohort study was conducted for 9 months after discharge of the patients. The patients were divided into a high-EE group and a low-EE group using a few cut-off points concerning the number of critical comments (CCs) and emotional over-involvement (EOI), the 9-month relapse risks were compared, and the relapse risk ratio and its 95% confidence interval were calculated. Also, the sensitivity, specificity, positive predictive value, and negative predictive value were calculated, and the optimal cut-off point was evaluated. Multiple logistic regression analysis was performed to control the effects of potential confounding factors. Results: When the subjects with three or more CCs, or an EOI score of three or higher were regarded as a high-EE group, and the others as a low-EE group, the nine-month relapse risks were 83.3% (5/6) and 19.2% (5/26), respectively, and the relapse risk ratio (95% confidence interval) was 4.3 (1.8-12.2). The values of the validity parameters were the highest with these cut-off points. The effect of EE was also significant on multiple logistic regression analysis. Limitations: Small sample size and severity of the patients. Conclusions: Families' EE based on CFI correlated with relapse also in Japan.
KW - Depression
KW - Expressed emotion
KW - Family
KW - Mood disorder
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U2 - 10.1016/S0165-0327(00)00185-3
DO - 10.1016/S0165-0327(00)00185-3
M3 - Article
C2 - 11246079
AN - SCOPUS:0035097241
VL - 63
SP - 43
EP - 49
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
SN - 0165-0327
IS - 1-3
ER -