Experimental animal models in Mongolian gerbils and mice

H. Isogai, E. Isogai, Kenji Yokota, K. Oguma

Research output: Contribution to journalArticle

Abstract

Helicobacter pylori is an emerging candidate agent for the genesis of chronic gastritis and peptic ulcer. There have been many challenges to establish an experimental infection with H. pylori in animals. In recent, several studies reported for animal infection with this organism. One of them was the study using urinary system. The study indicated the ability of H. pylori to induce inflammation without significant low pH condition. Experimental infection in Mongolian gerbils showed that H. pylori could colonize on the surface of the gastric mucosa in animals without human. The study of nude mice by Karita et al. showed several valuable facts concerning the relation between bacterial pathogenicity and potential of bacterial colonization in stomach. The study in which remaining of bacteria was extended showed that colonization of H. pylori was affected by bacterial flora in the stomach.

Original languageEnglish
Pages (from-to)3138-3143
Number of pages6
JournalNihon rinsho. Japanese journal of clinical medicine
Volume51
Issue number12
Publication statusPublished - Dec 1993
Externally publishedYes

Fingerprint

Gerbillinae
Helicobacter pylori
Animal Models
Stomach
Infection
Gastritis
Gastric Mucosa
Peptic Ulcer
Nude Mice
Virulence
Inflammation
Bacteria

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Experimental animal models in Mongolian gerbils and mice. / Isogai, H.; Isogai, E.; Yokota, Kenji; Oguma, K.

In: Nihon rinsho. Japanese journal of clinical medicine, Vol. 51, No. 12, 12.1993, p. 3138-3143.

Research output: Contribution to journalArticle

Isogai, H. ; Isogai, E. ; Yokota, Kenji ; Oguma, K. / Experimental animal models in Mongolian gerbils and mice. In: Nihon rinsho. Japanese journal of clinical medicine. 1993 ; Vol. 51, No. 12. pp. 3138-3143.
@article{bab057faabe44ec29b7878ac403fee23,
title = "Experimental animal models in Mongolian gerbils and mice",
abstract = "Helicobacter pylori is an emerging candidate agent for the genesis of chronic gastritis and peptic ulcer. There have been many challenges to establish an experimental infection with H. pylori in animals. In recent, several studies reported for animal infection with this organism. One of them was the study using urinary system. The study indicated the ability of H. pylori to induce inflammation without significant low pH condition. Experimental infection in Mongolian gerbils showed that H. pylori could colonize on the surface of the gastric mucosa in animals without human. The study of nude mice by Karita et al. showed several valuable facts concerning the relation between bacterial pathogenicity and potential of bacterial colonization in stomach. The study in which remaining of bacteria was extended showed that colonization of H. pylori was affected by bacterial flora in the stomach.",
author = "H. Isogai and E. Isogai and Kenji Yokota and K. Oguma",
year = "1993",
month = "12",
language = "English",
volume = "51",
pages = "3138--3143",
journal = "Nippon rinsho. Japanese journal of clinical medicine",
issn = "0047-1852",
publisher = "Nipponrinsho Co., Inc.",
number = "12",

}

TY - JOUR

T1 - Experimental animal models in Mongolian gerbils and mice

AU - Isogai, H.

AU - Isogai, E.

AU - Yokota, Kenji

AU - Oguma, K.

PY - 1993/12

Y1 - 1993/12

N2 - Helicobacter pylori is an emerging candidate agent for the genesis of chronic gastritis and peptic ulcer. There have been many challenges to establish an experimental infection with H. pylori in animals. In recent, several studies reported for animal infection with this organism. One of them was the study using urinary system. The study indicated the ability of H. pylori to induce inflammation without significant low pH condition. Experimental infection in Mongolian gerbils showed that H. pylori could colonize on the surface of the gastric mucosa in animals without human. The study of nude mice by Karita et al. showed several valuable facts concerning the relation between bacterial pathogenicity and potential of bacterial colonization in stomach. The study in which remaining of bacteria was extended showed that colonization of H. pylori was affected by bacterial flora in the stomach.

AB - Helicobacter pylori is an emerging candidate agent for the genesis of chronic gastritis and peptic ulcer. There have been many challenges to establish an experimental infection with H. pylori in animals. In recent, several studies reported for animal infection with this organism. One of them was the study using urinary system. The study indicated the ability of H. pylori to induce inflammation without significant low pH condition. Experimental infection in Mongolian gerbils showed that H. pylori could colonize on the surface of the gastric mucosa in animals without human. The study of nude mice by Karita et al. showed several valuable facts concerning the relation between bacterial pathogenicity and potential of bacterial colonization in stomach. The study in which remaining of bacteria was extended showed that colonization of H. pylori was affected by bacterial flora in the stomach.

UR - http://www.scopus.com/inward/record.url?scp=0027711690&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027711690&partnerID=8YFLogxK

M3 - Article

C2 - 8283621

AN - SCOPUS:0027711690

VL - 51

SP - 3138

EP - 3143

JO - Nippon rinsho. Japanese journal of clinical medicine

JF - Nippon rinsho. Japanese journal of clinical medicine

SN - 0047-1852

IS - 12

ER -