Exercise tolerance test in lung cancer patients: The relationship between exercise capacity and postthoracotomy hospital mortality

S. Miyoshi, K. Nakahara, K. Ohno, Y. Monden, Y. Kawashima

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

To evaluate the significance of the blood lactate threshold as a predictor of postthoracotomy hospital mortality resulting from pulmonary complications, a 3-minute incremental exercise test was administered to 33 lung cancer patients who underwent thoracotomy between October, 1981, and May, 1984. The oxygen consumption/body surface area at an arterial lactate level of 20 mg/dl (V̇O2/BSA at La-20) was adopted as the blood lactate threshold. Age and pulmonary function parameters such as forced expiratory volume in one second (FEV1)/body surface area (BSA), FEV1/forced vital capacity, diffusing capacity for the carbon monoxide/lung volume, and maximum ventilatory volume/BSA revealed significant differences between patients with postthoracotomy pulmonary complications and those without such complications. However, there was no difference in pulmonary function test results between the surviving and decreased patients. In contrast, although V̇O2/BSA at La-20 did not differ between the patients with and without pulmonary complications, it differed significantly between the surviving and deceased patients. We concluded that postthoracotomy pulmonary complications depended on the severity of preoperatively associated pulmonary function disorders and that the blood lactate threshold expressed by V̇O2/BSA at La-20 was an important indicator of the risk of hospital mortality.

Original languageEnglish
Pages (from-to)487-490
Number of pages4
JournalAnnals of Thoracic Surgery
Volume44
Issue number5
Publication statusPublished - 1987
Externally publishedYes

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Exercise Tolerance
Hospital Mortality
Exercise Test
Body Surface Area
Lung Neoplasms
Exercise
Lung
Lactic Acid
Respiratory Function Tests
Vital Capacity
Forced Expiratory Volume
Thoracotomy
Carbon Monoxide
Oxygen Consumption

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Exercise tolerance test in lung cancer patients : The relationship between exercise capacity and postthoracotomy hospital mortality. / Miyoshi, S.; Nakahara, K.; Ohno, K.; Monden, Y.; Kawashima, Y.

In: Annals of Thoracic Surgery, Vol. 44, No. 5, 1987, p. 487-490.

Research output: Contribution to journalArticle

Miyoshi, S. ; Nakahara, K. ; Ohno, K. ; Monden, Y. ; Kawashima, Y. / Exercise tolerance test in lung cancer patients : The relationship between exercise capacity and postthoracotomy hospital mortality. In: Annals of Thoracic Surgery. 1987 ; Vol. 44, No. 5. pp. 487-490.
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