Evolution of the wheat blast fungus through functional losses in a host specificity determinant

Yoshihiro Inoue, Trinh T.P. Vy, Kentaro Yoshida, Hokuto Asano, Chikako Mitsuoka, Soichiro Asuke, Vu L. Anh, Christian J.R. Cumagun, Izumi Chuma, Ryohei Terauchi, Kenji Kato, Thomas Mitchell, Barbara Valent, Mark Farman, Yukio Tosa

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Wheat blast first emerged in Brazil in the mid-1980s and has recently caused heavy crop losses in Asia. Here we show how this devastating pathogen evolved in Brazil. Genetic analysis of host species determinants in the blast fungus resulted in the cloning of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containing the corresponding resistance genes Rwt3 and Rwt4. Studies on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3. This implies that the rwt3 wheat served as a springboard for the host jump to common wheat.

Original languageEnglish
Pages (from-to)80-83
Number of pages4
JournalScience
Volume357
Issue number6346
DOIs
Publication statusPublished - Jul 7 2017

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Host Specificity
Triticum
Fungi
Brazil
Genes
Lolium
Organism Cloning

ASJC Scopus subject areas

  • Medicine(all)
  • General

Cite this

Inoue, Y., Vy, T. T. P., Yoshida, K., Asano, H., Mitsuoka, C., Asuke, S., ... Tosa, Y. (2017). Evolution of the wheat blast fungus through functional losses in a host specificity determinant. Science, 357(6346), 80-83. https://doi.org/10.1126/science.aam9654

Evolution of the wheat blast fungus through functional losses in a host specificity determinant. / Inoue, Yoshihiro; Vy, Trinh T.P.; Yoshida, Kentaro; Asano, Hokuto; Mitsuoka, Chikako; Asuke, Soichiro; Anh, Vu L.; Cumagun, Christian J.R.; Chuma, Izumi; Terauchi, Ryohei; Kato, Kenji; Mitchell, Thomas; Valent, Barbara; Farman, Mark; Tosa, Yukio.

In: Science, Vol. 357, No. 6346, 07.07.2017, p. 80-83.

Research output: Contribution to journalArticle

Inoue, Y, Vy, TTP, Yoshida, K, Asano, H, Mitsuoka, C, Asuke, S, Anh, VL, Cumagun, CJR, Chuma, I, Terauchi, R, Kato, K, Mitchell, T, Valent, B, Farman, M & Tosa, Y 2017, 'Evolution of the wheat blast fungus through functional losses in a host specificity determinant', Science, vol. 357, no. 6346, pp. 80-83. https://doi.org/10.1126/science.aam9654
Inoue Y, Vy TTP, Yoshida K, Asano H, Mitsuoka C, Asuke S et al. Evolution of the wheat blast fungus through functional losses in a host specificity determinant. Science. 2017 Jul 7;357(6346):80-83. https://doi.org/10.1126/science.aam9654
Inoue, Yoshihiro ; Vy, Trinh T.P. ; Yoshida, Kentaro ; Asano, Hokuto ; Mitsuoka, Chikako ; Asuke, Soichiro ; Anh, Vu L. ; Cumagun, Christian J.R. ; Chuma, Izumi ; Terauchi, Ryohei ; Kato, Kenji ; Mitchell, Thomas ; Valent, Barbara ; Farman, Mark ; Tosa, Yukio. / Evolution of the wheat blast fungus through functional losses in a host specificity determinant. In: Science. 2017 ; Vol. 357, No. 6346. pp. 80-83.
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