Evolution of pathogenicity controlled by small, dispensable chromosomes in Alternaria alternata pathogens

Takashi Tsuge, Yoshiaki Harimoto, Kosuke Hanada, Yasunori Akagi, Motoichiro Kodama, Kazuya Akimitsu, Mikihiro Yamamoto

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Alternaria alternata includes seven pathogenic variants, called pathotypes, which produce host-selective toxins (HSTs) as determinant factors for pathogenicity. The gene clusters for HST biosynthesis were identified from six pathotypes (Japanese pear, strawberry, tangerine, apple, tomato and rough lemon) and were found to reside on small chromosomes of <2.0 Mb in most strains tested. We isolated mutants lacking the small chromosomes from the strawberry, apple and tomato pathotypes and showed that the small chromosomes are dispensable for growth. In this review, we summarize our current understanding of the evolution of pathogenicity controlled by small, dispensable chromosomes in Alternaria alternata pathogens.

Original languageEnglish
Pages (from-to)27-31
Number of pages5
JournalPhysiological and Molecular Plant Pathology
Volume95
DOIs
Publication statusPublished - Jul 1 2016

Keywords

  • Alternaria alternata
  • Conditionally dispensable chromosome
  • Evolution
  • Host-selective toxin

ASJC Scopus subject areas

  • Genetics
  • Plant Science

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