Evaluation of the Magnetization Properties of Magnetic Nanoparticles in Serum Using HTS-SQUID

Ryota Isshiki; Yuta Nakamura; Shun Takeuchi; Tetsuro Hirata; Kenji Sakai; Toshihiko Kiwa; Keiji Tsukada

doi:10.1109/TASC.2018.2795619

Evaluation of the Magnetization Properties of Magnetic Nanoparticles in Serum Using HTS-SQUID

Ryota Isshiki, Yuta Nakamura, Shun Takeuchi, Tetsuro Hirata, Kenji Sakai, Toshihiko Kiwa, Keiji Tsukada

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The magnetization properties of magnetic nanoparticles (MNPs) changed by the action of the buffer and serum solutions with different viscosities were analyzed using dc and ac magnetometers that utilized high-temperature superconductivity-superconducting quantum interference devices. The magnetization properties of MNPs in different solutions with different viscosities were measured using a dc magnetometer via vibrating the sample under a dc magnetic field. The harmonic signal characteristics of the MNPs in different solutions were measured in a low-frequency magnetic field. In addition, the dynamic changes in the magnetic characteristics of MNPs in different solutions were measured using an ac magnetometer with a high frequency. The results corresponding to the low- and high-frequency fields showed that both viscosity of the solvent and the interactions between the MNPs and the solvent are important influencing factors in immunoassays using MNPs.

Original language	English
Article number	8264761
Journal	IEEE Transactions on Applied Superconductivity
Volume	28
Issue number	4
DOIs	https://doi.org/10.1109/TASC.2018.2795619
Publication status	Published - Jun 2018

Keywords

HTS-SQUID
magnetic nanoparticles
magnetization properties
viscosity

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Electrical and Electronic Engineering

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10.1109/TASC.2018.2795619

Cite this

@article{ed1de639d0364a019191c676860ad27f,

title = "Evaluation of the Magnetization Properties of Magnetic Nanoparticles in Serum Using HTS-SQUID",

abstract = "The magnetization properties of magnetic nanoparticles (MNPs) changed by the action of the buffer and serum solutions with different viscosities were analyzed using dc and ac magnetometers that utilized high-temperature superconductivity-superconducting quantum interference devices. The magnetization properties of MNPs in different solutions with different viscosities were measured using a dc magnetometer via vibrating the sample under a dc magnetic field. The harmonic signal characteristics of the MNPs in different solutions were measured in a low-frequency magnetic field. In addition, the dynamic changes in the magnetic characteristics of MNPs in different solutions were measured using an ac magnetometer with a high frequency. The results corresponding to the low- and high-frequency fields showed that both viscosity of the solvent and the interactions between the MNPs and the solvent are important influencing factors in immunoassays using MNPs.",

keywords = "HTS-SQUID, magnetic nanoparticles, magnetization properties, viscosity",

author = "Ryota Isshiki and Yuta Nakamura and Shun Takeuchi and Tetsuro Hirata and Kenji Sakai and Toshihiko Kiwa and Keiji Tsukada",

note = "Funding Information: Manuscript received September 18, 2017; accepted January 12, 2018. Date of publication January 23, 2018; date of current version February 8, 2018. This work was supported by the “Strategic Promotion of Innovative R&D” program funded by the Japan Science and Technology Agency. (Corresponding author: Ryota Isshiki.) The authors are with the Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan (e-mail: pysv5rpl@s. okayama-u.ac.jp; p1w51i0v@s.okayama-u.ac.jp; pa3w6btj@s.okayama-u. ac.jp; p1ok3h10@s.okayama-u.ac.jp; sakai-k@okayama-u.ac.jp; kiwa@ okayamau.ac.jp; tsukada@cc.okayama-u.ac.jp). Publisher Copyright: {\textcopyright} 2018 IEEE.",

year = "2018",

month = jun,

doi = "10.1109/TASC.2018.2795619",

language = "English",

volume = "28",

journal = "IEEE Transactions on Applied Superconductivity",

issn = "1051-8223",

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T1 - Evaluation of the Magnetization Properties of Magnetic Nanoparticles in Serum Using HTS-SQUID

AU - Isshiki, Ryota

AU - Nakamura, Yuta

AU - Takeuchi, Shun

AU - Hirata, Tetsuro

AU - Sakai, Kenji

AU - Kiwa, Toshihiko

AU - Tsukada, Keiji

N1 - Funding Information: Manuscript received September 18, 2017; accepted January 12, 2018. Date of publication January 23, 2018; date of current version February 8, 2018. This work was supported by the “Strategic Promotion of Innovative R&D” program funded by the Japan Science and Technology Agency. (Corresponding author: Ryota Isshiki.) The authors are with the Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan (e-mail: pysv5rpl@s. okayama-u.ac.jp; p1w51i0v@s.okayama-u.ac.jp; pa3w6btj@s.okayama-u. ac.jp; p1ok3h10@s.okayama-u.ac.jp; sakai-k@okayama-u.ac.jp; kiwa@ okayamau.ac.jp; tsukada@cc.okayama-u.ac.jp). Publisher Copyright: © 2018 IEEE.

PY - 2018/6

Y1 - 2018/6

N2 - The magnetization properties of magnetic nanoparticles (MNPs) changed by the action of the buffer and serum solutions with different viscosities were analyzed using dc and ac magnetometers that utilized high-temperature superconductivity-superconducting quantum interference devices. The magnetization properties of MNPs in different solutions with different viscosities were measured using a dc magnetometer via vibrating the sample under a dc magnetic field. The harmonic signal characteristics of the MNPs in different solutions were measured in a low-frequency magnetic field. In addition, the dynamic changes in the magnetic characteristics of MNPs in different solutions were measured using an ac magnetometer with a high frequency. The results corresponding to the low- and high-frequency fields showed that both viscosity of the solvent and the interactions between the MNPs and the solvent are important influencing factors in immunoassays using MNPs.

AB - The magnetization properties of magnetic nanoparticles (MNPs) changed by the action of the buffer and serum solutions with different viscosities were analyzed using dc and ac magnetometers that utilized high-temperature superconductivity-superconducting quantum interference devices. The magnetization properties of MNPs in different solutions with different viscosities were measured using a dc magnetometer via vibrating the sample under a dc magnetic field. The harmonic signal characteristics of the MNPs in different solutions were measured in a low-frequency magnetic field. In addition, the dynamic changes in the magnetic characteristics of MNPs in different solutions were measured using an ac magnetometer with a high frequency. The results corresponding to the low- and high-frequency fields showed that both viscosity of the solvent and the interactions between the MNPs and the solvent are important influencing factors in immunoassays using MNPs.

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KW - magnetic nanoparticles

KW - magnetization properties

KW - viscosity

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Evaluation of the Magnetization Properties of Magnetic Nanoparticles in Serum Using HTS-SQUID

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