Evaluation of the Magnetization Properties of Magnetic Nanoparticles in Serum Using HTS-SQUID

Ryota Isshiki, Yuta Nakamura, Shun Takeuchi, Tetsuro Hirata, Kenji Sakai, Toshihiko Kiwa, Keiji Tsukada

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The magnetization properties of magnetic nanoparticles (MNPs) changed by the action of the buffer and serum solutions with different viscosities were analyzed using dc and ac magnetometers that utilized high-temperature superconductivity-superconducting quantum interference devices. The magnetization properties of MNPs in different solutions with different viscosities were measured using a dc magnetometer via vibrating the sample under a dc magnetic field. The harmonic signal characteristics of the MNPs in different solutions were measured in a low-frequency magnetic field. In addition, the dynamic changes in the magnetic characteristics of MNPs in different solutions were measured using an ac magnetometer with a high frequency. The results corresponding to the low- and high-frequency fields showed that both viscosity of the solvent and the interactions between the MNPs and the solvent are important influencing factors in immunoassays using MNPs.

Original languageEnglish
Article number8264761
JournalIEEE Transactions on Applied Superconductivity
Volume28
Issue number4
DOIs
Publication statusPublished - Jun 1 2018

Keywords

  • HTS-SQUID
  • magnetic nanoparticles
  • magnetization properties
  • viscosity

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

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