Evaluation of soft tissue sarcomas response to preoperative treatment: Assessment by angiography, thallium scintigraphy, and dynamic MRI

Akira Kawai, Shinsuke Sugihara, Toshiyuki Kunisada, Osamu Sato, Hajime Inoue

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Assessment of the response of soft tissue sarcomas to preoperative treatment is of significant clinical importance. However, there are few reports concerning the accuracy of each imaging technique in assessing the response of soft tissue sarcomas to preoperative treatment. Methods: The responses of 15 soft tissue sarcomas to preoperative treatment by digital subtraction angiography, thallium scintigraphy, and dynamic magnetic resonance imaging (MRI) were compared with histologic evaluation of the resected specimens. Tumors with at least 90% histologic necrosis were considered to be effectively treated. Results: The accuracy of each assessment technique was 58.3% for digital subtraction angiography, 80% for thallium scintigraphy, and 77.8% for dynamic MRI. Both the differences in slope before and after treatment and the posttreatment slope values of dynamic MRI correlated with the histologic responses. Conclusion: Thallium scintigraphy and dynamic MRI showed sufficient value in the assessment of soft tissue sarcomas responses to preoperative treatment. Dynamic MRI had major advantages in its quantitative and spatial resolutions.

Original languageEnglish
Pages (from-to)93-99
Number of pages7
JournalInternational Journal of Clinical Oncology
Volume1
Issue number2
Publication statusPublished - Aug 1996

Fingerprint

Thallium
Radionuclide Imaging
Sarcoma
Angiography
Magnetic Resonance Imaging
Digital Subtraction Angiography
Necrosis
Neoplasms

Keywords

  • Angiography
  • Dynamic MRI
  • Histologic effect
  • Preoperative treatment
  • Soft tissue sarcoma
  • Thallium scintigraphy

ASJC Scopus subject areas

  • Oncology

Cite this

Evaluation of soft tissue sarcomas response to preoperative treatment : Assessment by angiography, thallium scintigraphy, and dynamic MRI. / Kawai, Akira; Sugihara, Shinsuke; Kunisada, Toshiyuki; Sato, Osamu; Inoue, Hajime.

In: International Journal of Clinical Oncology, Vol. 1, No. 2, 08.1996, p. 93-99.

Research output: Contribution to journalArticle

@article{9c89e59ab25c4c6d99490f173ea89c8d,
title = "Evaluation of soft tissue sarcomas response to preoperative treatment: Assessment by angiography, thallium scintigraphy, and dynamic MRI",
abstract = "Background: Assessment of the response of soft tissue sarcomas to preoperative treatment is of significant clinical importance. However, there are few reports concerning the accuracy of each imaging technique in assessing the response of soft tissue sarcomas to preoperative treatment. Methods: The responses of 15 soft tissue sarcomas to preoperative treatment by digital subtraction angiography, thallium scintigraphy, and dynamic magnetic resonance imaging (MRI) were compared with histologic evaluation of the resected specimens. Tumors with at least 90{\%} histologic necrosis were considered to be effectively treated. Results: The accuracy of each assessment technique was 58.3{\%} for digital subtraction angiography, 80{\%} for thallium scintigraphy, and 77.8{\%} for dynamic MRI. Both the differences in slope before and after treatment and the posttreatment slope values of dynamic MRI correlated with the histologic responses. Conclusion: Thallium scintigraphy and dynamic MRI showed sufficient value in the assessment of soft tissue sarcomas responses to preoperative treatment. Dynamic MRI had major advantages in its quantitative and spatial resolutions.",
keywords = "Angiography, Dynamic MRI, Histologic effect, Preoperative treatment, Soft tissue sarcoma, Thallium scintigraphy",
author = "Akira Kawai and Shinsuke Sugihara and Toshiyuki Kunisada and Osamu Sato and Hajime Inoue",
year = "1996",
month = "8",
language = "English",
volume = "1",
pages = "93--99",
journal = "International Journal of Clinical Oncology",
issn = "1341-9625",
publisher = "Springer Japan",
number = "2",

}

TY - JOUR

T1 - Evaluation of soft tissue sarcomas response to preoperative treatment

T2 - Assessment by angiography, thallium scintigraphy, and dynamic MRI

AU - Kawai, Akira

AU - Sugihara, Shinsuke

AU - Kunisada, Toshiyuki

AU - Sato, Osamu

AU - Inoue, Hajime

PY - 1996/8

Y1 - 1996/8

N2 - Background: Assessment of the response of soft tissue sarcomas to preoperative treatment is of significant clinical importance. However, there are few reports concerning the accuracy of each imaging technique in assessing the response of soft tissue sarcomas to preoperative treatment. Methods: The responses of 15 soft tissue sarcomas to preoperative treatment by digital subtraction angiography, thallium scintigraphy, and dynamic magnetic resonance imaging (MRI) were compared with histologic evaluation of the resected specimens. Tumors with at least 90% histologic necrosis were considered to be effectively treated. Results: The accuracy of each assessment technique was 58.3% for digital subtraction angiography, 80% for thallium scintigraphy, and 77.8% for dynamic MRI. Both the differences in slope before and after treatment and the posttreatment slope values of dynamic MRI correlated with the histologic responses. Conclusion: Thallium scintigraphy and dynamic MRI showed sufficient value in the assessment of soft tissue sarcomas responses to preoperative treatment. Dynamic MRI had major advantages in its quantitative and spatial resolutions.

AB - Background: Assessment of the response of soft tissue sarcomas to preoperative treatment is of significant clinical importance. However, there are few reports concerning the accuracy of each imaging technique in assessing the response of soft tissue sarcomas to preoperative treatment. Methods: The responses of 15 soft tissue sarcomas to preoperative treatment by digital subtraction angiography, thallium scintigraphy, and dynamic magnetic resonance imaging (MRI) were compared with histologic evaluation of the resected specimens. Tumors with at least 90% histologic necrosis were considered to be effectively treated. Results: The accuracy of each assessment technique was 58.3% for digital subtraction angiography, 80% for thallium scintigraphy, and 77.8% for dynamic MRI. Both the differences in slope before and after treatment and the posttreatment slope values of dynamic MRI correlated with the histologic responses. Conclusion: Thallium scintigraphy and dynamic MRI showed sufficient value in the assessment of soft tissue sarcomas responses to preoperative treatment. Dynamic MRI had major advantages in its quantitative and spatial resolutions.

KW - Angiography

KW - Dynamic MRI

KW - Histologic effect

KW - Preoperative treatment

KW - Soft tissue sarcoma

KW - Thallium scintigraphy

UR - http://www.scopus.com/inward/record.url?scp=7844237683&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=7844237683&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:7844237683

VL - 1

SP - 93

EP - 99

JO - International Journal of Clinical Oncology

JF - International Journal of Clinical Oncology

SN - 1341-9625

IS - 2

ER -