Evaluation of several fluorinated ATPH derivatives as functionalized Lewis acid receptors for conjugate alkylation to α,β-unsaturated aldehydes with alkyllithium nucleophiles

Takashi Ooi, Yuichiro Kondo, Tomoya Miura, Keiji Maruoka

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Several fluorinated aluminum tris(2,6-diphenylphenoxide) (ATPH) derivatives have been synthesized to evaluate, as functionalized Lewis acid receptors, the conjugate alkylation ability to α,β-unsaturated aldehydes by the combined use of alkyllithium nucleophiles. Among these, 3,4,5-F3-ATPH was found to be the most satisfactory.

Original languageEnglish
Pages (from-to)3951-3954
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number22
DOIs
Publication statusPublished - Jun 2 1997
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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