Evaluation of Rheumatoid Arthritis Using a Scoring System Devised from Magnetic Resonance Imaging of Rheumatoid Knees

Kazuhiro Takeuchi, Hajime Inoue, Yoshiki Yokoyama, Masuo Senda, Yusuke Ota, Nobuhiro Abe, Keiichiro Nishida

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We studied the magnetic resonance imaging (MRI) of 120 knees in 86 rheumatoid arthritis (RA) patients and of 14 unaffected knees in 12 control cases. We also developed a scoring system as a quantitative analysis method. We divided the MRI into 10 items, and classified the severity of the symptoms into 4 grades (score 0 to 3). The average total score increased according to the radiographic grade. Soft tissue lesions were clearly detected, even in the early stages of RA. Items such as synovial proliferation showed a high score even in the early stages, suggesting that it was the initial symptom of RA. The score also showed a correlation with the inflammatory signs. These results suggest that this scoring system is very sensitive and yields a good reflection of RA activity. We demonstrated that this system is simple and convenient for routine diagnostic use. We further demonstrated that it is useful for following the advancement of RA and for evaluating the response to treatment.

Original languageEnglish
Pages (from-to)211-224
Number of pages14
JournalActa medica Okayama
Volume52
Issue number4
Publication statusPublished - Aug 1 1998

Keywords

  • Magnetic resonance imaging
  • Rheumatoid arthritis
  • Scoring system
  • Synovial membrane

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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