Evaluation of mucosal healing of ulcerative colitis by a quantitative fecal immunochemical test

Asuka Nakarai, Jun Kato, Sakiko Hiraoka, Motoaki Kuriyama, Mitsuhiro Akita, Tomoko Hirakawa, Hiroyuki Okada, Kazuhide Yamamoto

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Objectives: Accumulating evidence has underlined the importance of mucosal healing as a treatment goal for ulcerative colitis (UC). Quantitative fecal immunochemical tests (FITs), which can rapidly quantify fecal blood with automated equipment, have been used recently to screen for colorectal neoplasia. The aim of this study is to determine whether an FIT can evaluate mucosal healing in UC. Methods: Feces collected from UC patients who underwent colonoscopy were examined by FITs, and results were compared with colonoscopic findings. Mucosal status was assessed using the Mayo endoscopic subscore classification. Maximum score for the colorectum in each patient was recorded. Results: Evaluated were FIT results in conjunction with 310 colonoscopies that were performed in 152 UC patients. A large majority of patients with a Mayo 0 endoscopic score had negative FIT (

Original languageEnglish
Pages (from-to)83-89
Number of pages7
JournalAmerican Journal of Gastroenterology
Volume108
Issue number1
DOIs
Publication statusPublished - Jan 2013

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Ulcerative Colitis
Colonoscopy
Feces
Equipment and Supplies
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

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Evaluation of mucosal healing of ulcerative colitis by a quantitative fecal immunochemical test. / Nakarai, Asuka; Kato, Jun; Hiraoka, Sakiko; Kuriyama, Motoaki; Akita, Mitsuhiro; Hirakawa, Tomoko; Okada, Hiroyuki; Yamamoto, Kazuhide.

In: American Journal of Gastroenterology, Vol. 108, No. 1, 01.2013, p. 83-89.

Research output: Contribution to journalArticle

Nakarai, Asuka ; Kato, Jun ; Hiraoka, Sakiko ; Kuriyama, Motoaki ; Akita, Mitsuhiro ; Hirakawa, Tomoko ; Okada, Hiroyuki ; Yamamoto, Kazuhide. / Evaluation of mucosal healing of ulcerative colitis by a quantitative fecal immunochemical test. In: American Journal of Gastroenterology. 2013 ; Vol. 108, No. 1. pp. 83-89.
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