TY - JOUR
T1 - Evaluation of Lung Radiofrequency Ablation with Dual-Energy Computed Tomography
T2 - Analysis of Tumor Composition and Lung Perfusion
AU - Tomita, Koji
AU - Hiraki, Takao
AU - Gobara, Hideo
AU - Fujiwara, Hiroyasu
AU - Iguchi, Toshihiro
AU - Matsui, Yusuke
AU - Kanazawa, Susumu
N1 - Publisher Copyright:
Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Objective The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. Methods The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Z eff) of the tumors before RFA was compared with the Z eff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. Results The mean Z eff of the tumors significantly (P < 0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. Conclusions Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.
AB - Objective The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. Methods The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Z eff) of the tumors before RFA was compared with the Z eff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. Results The mean Z eff of the tumors significantly (P < 0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. Conclusions Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.
KW - composition analysis
KW - dual-energy computed tomography
KW - lung perfusion
KW - lung radiofrequency ablation
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U2 - 10.1097/RCT.0000000000000422
DO - 10.1097/RCT.0000000000000422
M3 - Article
C2 - 27224234
AN - SCOPUS:84969960222
VL - 40
SP - 752
EP - 756
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
SN - 0363-8715
IS - 5
ER -