Evaluation of Lung Radiofrequency Ablation With Dual-Energy Computed Tomography: Analysis of Tumor Composition and Lung Perfusion

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. METHODS: The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Zeff) of the tumors before RFA was compared with the Zeff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. RESULTS: The mean Zeff of the tumors significantly (P <0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. CONCLUSIONS: Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.

Original languageEnglish
JournalJournal of Computer Assisted Tomography
DOIs
Publication statusAccepted/In press - May 25 2016

Fingerprint

Perfusion
Tomography
Lung
Neoplasms
Perfusion Imaging
Radionuclide Imaging
Iodine

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

@article{8467cc77924d49509a2c7d01b72c864e,
title = "Evaluation of Lung Radiofrequency Ablation With Dual-Energy Computed Tomography: Analysis of Tumor Composition and Lung Perfusion",
abstract = "OBJECTIVE: The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. METHODS: The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Zeff) of the tumors before RFA was compared with the Zeff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. RESULTS: The mean Zeff of the tumors significantly (P <0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. CONCLUSIONS: Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.",
author = "Koji Tomita and Takao Hiraki and Hideo Gobara and Hiroyasu Fujiwara and Toshihiro Iguchi and Yusuke Matsui and Susumu Kanazawa",
year = "2016",
month = "5",
day = "25",
doi = "10.1097/RCT.0000000000000422",
language = "English",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Evaluation of Lung Radiofrequency Ablation With Dual-Energy Computed Tomography

T2 - Analysis of Tumor Composition and Lung Perfusion

AU - Tomita, Koji

AU - Hiraki, Takao

AU - Gobara, Hideo

AU - Fujiwara, Hiroyasu

AU - Iguchi, Toshihiro

AU - Matsui, Yusuke

AU - Kanazawa, Susumu

PY - 2016/5/25

Y1 - 2016/5/25

N2 - OBJECTIVE: The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. METHODS: The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Zeff) of the tumors before RFA was compared with the Zeff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. RESULTS: The mean Zeff of the tumors significantly (P <0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. CONCLUSIONS: Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.

AB - OBJECTIVE: The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. METHODS: The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Zeff) of the tumors before RFA was compared with the Zeff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. RESULTS: The mean Zeff of the tumors significantly (P <0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. CONCLUSIONS: Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.

UR - http://www.scopus.com/inward/record.url?scp=84969960222&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84969960222&partnerID=8YFLogxK

U2 - 10.1097/RCT.0000000000000422

DO - 10.1097/RCT.0000000000000422

M3 - Article

C2 - 27224234

AN - SCOPUS:84969960222

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

ER -