Evaluation of Lumbar Bone Mineral Density by Dual Energy X‐Ray Absorptiometry

Hirokazu Tsukahara, Tetsuo Nakashima, Masahiro Yoshimoto, Masanori Kuriyama, Yosuke Shigematsu, Shuhei Hayashi, Shinichi Haruki, Yasushi Ishii, Masakatsu Sudo

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Using dual‐energy x‐ray absorptiometry (DEXA), the lumbar spinal bone mineral density (BMD) in 49 Japanese children with or without metabolic bone disease (MBD) was determined. The following results were obtained: (a) The normal data for healthy Caucasians (J Clin Endocrinol Metab 1990; 70: 1330‐1333) appear to be applicable to Japanese children; (b) BMD was normal in patients with congenital hydronephrosis with normal renal function; (c) One patient with congenital renal failure and one with Lowe syndrome had low BMD, but the MBD in the former improved markedly with peritoneal dialysis; (d) A reduced BMD was found in patients treated with long‐term steroids, probably because of decreased turnover of bone; (e) A reduction in BMD was pronounced in preterm infants during the first few months of life. In conclusion, DEXA is a useful method of bone densitometry in MBD in children.

Original languageEnglish
Pages (from-to)459-466
Number of pages8
JournalPediatrics International
Issue number4
Publication statusPublished - Aug 1991
Externally publishedYes


  • Dual‐energy x‐ray absorptiometry
  • Lumbar bone mineral density
  • Metabolic bone disease
  • Metabolic bone disease in preterm infants
  • Steroid‐induced osteoporosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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