Evaluation of effect of lung resection on lobar ventilation and perfusion using intrabronchial capnography

Tatsuya Yoshimasu, Shinichiro Miyoshi, Shinji Maebeya, Issei Hirai, Yasuaki Naito

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Intrabronchial capnography was applied in 11 lung cancer patients to investigate the effects of lobectomy on regional lung function. Spirometry and intrabronchial capnography were performed before surgery (PRE), and during the early (POST1, 19±5 POD) and late (POST2, 184±98 POD) postoperative periods. End-tidal carbon dioxide concentration (EtCO2) and Smidt's velocity profile index (V-index) were calculated from each lobar capnogram obtained bronchoscopically. The V-index of lobes without cancer on the operated-on side increased after surgery (PRE, 10.7±5.0%; POST1, 14.3±9.4%, NS; POST2, 16.8±8.6%, p<0.05), while the V-index on the unoperated-on side decreased after surgery (PRE, 10.5±5.3%; POST1, 7.9±3.5%, p<0.05; POST2, 7.2±2.9%, p<0.05). EtCO2 after surgery was lower on the operated-on side (POST1, 5.1±1.1%; POST2, 4.6±1.1%) than on the unoperated-on side (POST1, 5.4±0.9%, p<0.05; POST2, 5.0±0.9%, p<0.01). Since the V-index and EtCO2 are compatible with the expiratory flow rate and the perfusion/ventilation ratio, respectively, we concluded that the air flow decreased on the operated-onside and increased on the unoperated-on side postoperatively and that perfusion on the operated-on side was more severely reduced than ventilation. These findings suggest that intrabronchial capnography is useful for assessing the ventilation and perfusion of the individual lobes as single units.

Original languageEnglish
Pages (from-to)25-30
Number of pages6
JournalChest
Volume109
Issue number1
DOIs
Publication statusPublished - Jan 1 1996

Keywords

  • bronchoscopy
  • capnography
  • lung cancer
  • lung resection
  • regional lung function

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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