Evaluation of blood-filling patterns in schlemm canal for trabectome surgery

Kae Sugihara, Akiko Narita, Naruka Mitsui, Seido Okuda, Jiro Seguchi, Yuki Morizane

Research output: Contribution to journalArticlepeer-review

Abstract

Précis:Regardless of the blood-filling patterns in Schlemm canal (SC) before the trabecular meshwork (TM) ablation, the trabectome surgery, combined with phacoemulsification, is effective for mild to moderate primary open-angle glaucoma patients.Purpose:The purpose of this study was to evaluate the association between trabectome surgery outcomes and the blood filling patterns in SC before TM ablation.Materials and Methods:This retrospective cohort study included 105 eyes of 84 Japanese primary open-angle glaucoma patients who had undergone trabectome surgery in combination with cataract surgery. Provocative gonioscopy was performed before TM ablation to classify the blood filling patterns in SC into 3 groups: no filling (group 1); patchy/irregular filling (group 2); and complete filling (group 3). The subjects were divided into 3 groups according to the blood filling patterns and the trabectome surgery outcomes were compared, including intraocular pressure (IOP), the percentage reduction in IOP, surgical success rate, and the number of glaucoma medications. Success was defined by IOP ≤15 mm Hg and a >20% reduction in IOP with/without glaucoma medication, and without additional glaucoma surgery after trabectome surgery combined with cataract surgery.Results:Twenty-four eyes were assigned to group 1, 48 to group 2, and 33 to group 3. Between-group analyses showed no significant intergroup differences in age (P=0.213), preoperative mean deviation (P=0.505), preoperative and postoperative IOP (P=0.941 and 0.458, respectively), preoperative and postoperative number of glaucoma medications (P=0.805 and 0.077, respectively), percentage IOP reduction (P=0.256), and success rates (P=0.540).Conclusion:Trabectome surgery is effective for mild to moderate primary open-angle glaucoma patients, independent of the blood-filling patterns in SC before the TM ablation.

Original languageEnglish
Pages (from-to)1101-1105
Number of pages5
JournalJournal of Glaucoma
Volume29
Issue number12
DOIs
Publication statusPublished - Dec 2020

Keywords

  • Blood reflux
  • Minimally invasive glaucoma surgery
  • Schlemm canal
  • Trabectome

ASJC Scopus subject areas

  • Ophthalmology

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