Abstract
This study aimed to investigate whether swept source optical coherence tomography (SS-OCT) could estimate the lesion depth and mineral loss quantitatively without the use of polarization sensitivity, and to examine a relationship between OCT data and transverse microradiography (TMR) lesion parameters. Twenty-four b vine root dentin specimens were allocated to three groups of 4-, 7-, and 14-day demineralization. Cross-sectional images of the specimens before and after the demineralization were captured by OCT at 1319 nm center wavelength. Following the demineralization, these specimens were cut into sections for TMR analysis. Correlations between the OCT data and TMR lesion parameters were examined. TMR images of the specimens showed cavitated lesions (lesion depth or LDTMR: 200 to 500 μm, ∧Z or mineral loss: 10,000 to 30,000 vol % í). acute OCT images showed "boundaries," suggesting the lesion front. Integrated dB values before and after the demineralization and their difference (RD, RS, and ∧R, respectively) were calculated from the lesion surface to the corrected depth of boundary (LDOCT). A statistically significant correlation was found between LDOCT and LDTMR (p < 0.05, r = 0.68). Similarly, statistically significant correlations were found between ∧Z and RD or ∧R. The OCT showed a potential for quantitative estimation of lesion depth and mineral loss with cavitated dentin lesions in vitro.
| Original language | English |
|---|---|
| Article number | 071408 |
| Journal | Journal of Biomedical Optics |
| Volume | 16 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2011 |
| Externally published | Yes |
Fingerprint
Keywords
- Demineralization
- Dentin
- Diagnosis
- Swept source optical coherence tomography
- Transverse microradiography
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Biomaterials
- Biomedical Engineering
Cite this
Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography. / Natsume, Yuko; Nakashima, Syozi; Sadr, Alireza; Shimada, Yasushi; Tagami, Junji; Sumi, Yasunori.
In: Journal of Biomedical Optics, Vol. 16, No. 7, 071408, 07.2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Estimation of lesion progress in artificial root caries by swept source optical coherence tomography in comparison to transverse microradiography
AU - Natsume, Yuko
AU - Nakashima, Syozi
AU - Sadr, Alireza
AU - Shimada, Yasushi
AU - Tagami, Junji
AU - Sumi, Yasunori
PY - 2011/7
Y1 - 2011/7
N2 - This study aimed to investigate whether swept source optical coherence tomography (SS-OCT) could estimate the lesion depth and mineral loss quantitatively without the use of polarization sensitivity, and to examine a relationship between OCT data and transverse microradiography (TMR) lesion parameters. Twenty-four b vine root dentin specimens were allocated to three groups of 4-, 7-, and 14-day demineralization. Cross-sectional images of the specimens before and after the demineralization were captured by OCT at 1319 nm center wavelength. Following the demineralization, these specimens were cut into sections for TMR analysis. Correlations between the OCT data and TMR lesion parameters were examined. TMR images of the specimens showed cavitated lesions (lesion depth or LDTMR: 200 to 500 μm, ∧Z or mineral loss: 10,000 to 30,000 vol % í). acute OCT images showed "boundaries," suggesting the lesion front. Integrated dB values before and after the demineralization and their difference (RD, RS, and ∧R, respectively) were calculated from the lesion surface to the corrected depth of boundary (LDOCT). A statistically significant correlation was found between LDOCT and LDTMR (p < 0.05, r = 0.68). Similarly, statistically significant correlations were found between ∧Z and RD or ∧R. The OCT showed a potential for quantitative estimation of lesion depth and mineral loss with cavitated dentin lesions in vitro.
AB - This study aimed to investigate whether swept source optical coherence tomography (SS-OCT) could estimate the lesion depth and mineral loss quantitatively without the use of polarization sensitivity, and to examine a relationship between OCT data and transverse microradiography (TMR) lesion parameters. Twenty-four b vine root dentin specimens were allocated to three groups of 4-, 7-, and 14-day demineralization. Cross-sectional images of the specimens before and after the demineralization were captured by OCT at 1319 nm center wavelength. Following the demineralization, these specimens were cut into sections for TMR analysis. Correlations between the OCT data and TMR lesion parameters were examined. TMR images of the specimens showed cavitated lesions (lesion depth or LDTMR: 200 to 500 μm, ∧Z or mineral loss: 10,000 to 30,000 vol % í). acute OCT images showed "boundaries," suggesting the lesion front. Integrated dB values before and after the demineralization and their difference (RD, RS, and ∧R, respectively) were calculated from the lesion surface to the corrected depth of boundary (LDOCT). A statistically significant correlation was found between LDOCT and LDTMR (p < 0.05, r = 0.68). Similarly, statistically significant correlations were found between ∧Z and RD or ∧R. The OCT showed a potential for quantitative estimation of lesion depth and mineral loss with cavitated dentin lesions in vitro.
KW - Demineralization
KW - Dentin
KW - Diagnosis
KW - Swept source optical coherence tomography
KW - Transverse microradiography
UR - http://www.scopus.com/inward/record.url?scp=80455163156&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80455163156&partnerID=8YFLogxK
U2 - 10.1117/1.3600448
DO - 10.1117/1.3600448
M3 - Article
C2 - 21806254
AN - SCOPUS:80455163156
VL - 16
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
SN - 1083-3668
IS - 7
M1 - 071408
ER -