Estimating the minimum stimulation frequency necessary to evoke tetanic progression based on muscle twitch parameters

Shogo Watanabe, Shinichi Fukuhara, Takeshi Fujinaga, Hisao Oka

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The summation of the muscle force caused by an increase in the firing rate is named a tetanic contraction (tetanus), and the minimum stimulation frequency necessary to evoke an unfused/fused tetanus is related to the contraction time (CT) and relaxation time (RT) of the twitch. In particular, the fusion index (FI) is a very useful indicator, and it is used to evaluate the change in the muscle fiber component ratio. However, the measurement of the FI is invasive, because most patients experience pain during the electrical stimulation for tetanus. We expect that the twitch parameters CT and RT can substitute for the FI in the future. We found that the minimum stimulation frequency necessary to evoke the unfused/fused tetanus can be estimated from the twitch parameters as a first step. The results showed that (1) the minimum stimulation frequencies calculated from twitch parameters during unfused/fused tetanus were very similar to those calculated from FI parameters, and (2) they were also strongly correlated with FI parameters regardless of fiber components. The basic characteristics of tetanic progression in different fiber types could be estimated from twitch parameters.

Original languageEnglish
Pages (from-to)466-476
Number of pages11
JournalPhysiological Measurement
Volume38
Issue number3
DOIs
Publication statusPublished - Feb 7 2017

Fingerprint

Tetanus
Muscle
Fusion reactions
Muscles
Relaxation time
Fibers
Electric Stimulation
Pain

Keywords

  • fiber type
  • muscle force
  • tetanus
  • twitch

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Physiology (medical)

Cite this

Estimating the minimum stimulation frequency necessary to evoke tetanic progression based on muscle twitch parameters. / Watanabe, Shogo; Fukuhara, Shinichi; Fujinaga, Takeshi; Oka, Hisao.

In: Physiological Measurement, Vol. 38, No. 3, 07.02.2017, p. 466-476.

Research output: Contribution to journalArticle

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