Escape of red blood cells through gaps in glomerular basement membrane in a patient with mixed connective tissue disease

Hirofiumi Makino, Isao Kumagai, Kazue Hironaka, Kosuke Ota, Kenichi Shikata, Zensuke Ota

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Hematuria in patients with glomerulonephritis seems to result from the passage of red blood cells through anatomical gaps in the glomerular basement membrane. However, such morphological evidence has rarely been demonstrated. A patient with mixed connective tissue disease associated with membranous glomerulonephritis is described in whom the renal biopsy specimen showed an escape of red blood cells through a gap in the basement membrane. These findings support the morphological basis of hematuria in glomerulonephritis.

Original languageEnglish
Pages (from-to)168-171
Number of pages4
JournalAmerican Journal of Nephrology
Volume15
Issue number2
DOIs
Publication statusPublished - Jan 1 1995

Keywords

  • Electron microscopy
  • Glomerular basement membrane
  • Hematuria
  • Membranous glomerulonephritis
  • Mixed connective tissue disease
  • Red blood cell

ASJC Scopus subject areas

  • Nephrology

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