Epithelium-poor type central odontogenic fibroma: An immunohistological study and review of the literature

Takashi Kimura, Seigo Ohba, Hitoshi Yoshimura, Naoki Katase, Yoshiaki Imamura, Takaaki Ueno, Hitoshi Nagatsuka, Kazuo Sano

Research output: Contribution to journalArticle

Abstract

The object of this study was to determine the characteristics of central odontogenic fibroma (COF) in order to help achieve a correct diagnosis. Central odontogenic fibroma, which tends to be epithelium-poor, is an extremely rare type of odontogenic fibroma. The lack of data concerning COF, due to its low incidence, can make this entity difficult to diagnose. We herein report an epithelium-poor type of COF of the mandible, which we examined immunohistologically. We also provide a review of the previous English literature to expand the knowledge about this disease. Positive reactions for vimentin and negative reactions for desmin andα-smooth muscle actin (α-SMA) in COFs were common findings in the previous reports. We also noted similar immunohistological findings. Our data (vimentin positive,α-SMA and desmin negative) should contribute to correctly diagnosing epithelium-poor type COF.

Original languageEnglish
Pages (from-to)273-278
Number of pages6
JournalJournal of Hard Tissue Biology
Volume22
Issue number2
DOIs
Publication statusPublished - 2013

Fingerprint

Desmin
Fibroma
Vimentin
Epithelium
Muscle
Actins
Literature
Mandible
Smooth Muscle
Incidence

Keywords

  • Central odontogenic fibroma
  • Epithelium-poor type
  • Mandible

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Biomaterials
  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Dentistry(all)

Cite this

Epithelium-poor type central odontogenic fibroma : An immunohistological study and review of the literature. / Kimura, Takashi; Ohba, Seigo; Yoshimura, Hitoshi; Katase, Naoki; Imamura, Yoshiaki; Ueno, Takaaki; Nagatsuka, Hitoshi; Sano, Kazuo.

In: Journal of Hard Tissue Biology, Vol. 22, No. 2, 2013, p. 273-278.

Research output: Contribution to journalArticle

Kimura, Takashi ; Ohba, Seigo ; Yoshimura, Hitoshi ; Katase, Naoki ; Imamura, Yoshiaki ; Ueno, Takaaki ; Nagatsuka, Hitoshi ; Sano, Kazuo. / Epithelium-poor type central odontogenic fibroma : An immunohistological study and review of the literature. In: Journal of Hard Tissue Biology. 2013 ; Vol. 22, No. 2. pp. 273-278.
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