TY - JOUR
T1 - Eosinophilic cholangitis with initial clinical features indistinguishable from IgG4-related cholangitis
AU - Iwamuro, Masaya
AU - Yamamoto, Kazuhide
AU - Kawamoto, Hirofumi
AU - Terada, Ryo
AU - Ogawa, Tsuneyoshi
AU - Nose, Soichiro
PY - 2009
Y1 - 2009
N2 - A 66-year-old woman presented with jaundice, elevated liver enzymes, peripheral eosinophilia and increased levels of immunoglobulin (Ig) G4. The image findings of the biliary tree revealed multifocal strictures mimicking primary sclerosing cholangitis. A biopsy specimen of the liver demonstrated an infiltration of inflammatory cells consisting of several eosinophils and IgG4-positive plasma cells. The liver enzymes and eosinophil count were normalized immediately after the administration of an oral steroid. Finally, the patient was diagnosed with eosinophilic cholangitis based on the clinical manifestations, although she had features of both eosinophilic cholangitis and IgG4-related cholangitis. This case indicates that the two entities may show similar manifestations and thus they should be discriminated carefully.
AB - A 66-year-old woman presented with jaundice, elevated liver enzymes, peripheral eosinophilia and increased levels of immunoglobulin (Ig) G4. The image findings of the biliary tree revealed multifocal strictures mimicking primary sclerosing cholangitis. A biopsy specimen of the liver demonstrated an infiltration of inflammatory cells consisting of several eosinophils and IgG4-positive plasma cells. The liver enzymes and eosinophil count were normalized immediately after the administration of an oral steroid. Finally, the patient was diagnosed with eosinophilic cholangitis based on the clinical manifestations, although she had features of both eosinophilic cholangitis and IgG4-related cholangitis. This case indicates that the two entities may show similar manifestations and thus they should be discriminated carefully.
KW - Autoimmune pancreatitis
KW - Eosinophilia
KW - Eosinophilic cholangitis
KW - IgG4-related cholangitis
KW - Sclerosing cholangitis
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U2 - 10.2169/internalmedicine.48.1892
DO - 10.2169/internalmedicine.48.1892
M3 - Article
C2 - 19571447
AN - SCOPUS:67650690828
VL - 48
SP - 1143
EP - 1147
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 13
ER -