Enhancement of MAMP signaling by chimeric receptors improves disease resistance in plants

Kyutaro Kishimoto, Yusuke Kouzai, Hanae Kaku, Naoto Shibuya, Eiichi Minami, Yoko Nishizawa

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Plants activate defense responses through the recognition of microbe-associated molecular patterns (MAMPs). Recently, several pattern-recognition receptors (PRRs) have been identified in plants, paving the way for manipulating MAMP signaling. CEBiP is a receptor for the chitin elicitor (CE) identified in the rice plasma membrane and XA21 is a member of the receptor-like protein kinase (RLK) family that confers disease resistance to rice bacterial leaf blight expressing the sulfated protein Ax21. To improve resistance to rice blast, the most serious fungal disease of rice, we aimed to create a defense system that combines high affinity of CEBiP for CE and the ability of XA21 to confer disease resistance. Cultured rice cells expressing the chimeric receptor CRXA, which consists of CEBiP and the intracellular region of XA21, induced cell death accompanied by an increased production of reactive oxygen and nitrogen species after exposure to CE. Rice plants expressing the chimeric receptor exhibited more resistance to rice blast. Engineering PRRs may be a new strategy in molecular breeding for achieving disease resistance.

Original languageEnglish
Pages (from-to)449-451
Number of pages3
JournalPlant Signaling and Behavior
Volume6
Issue number3
DOIs
Publication statusPublished - Mar 2011
Externally publishedYes

Fingerprint

disease resistance
microorganisms
receptors
rice
chitin
blast disease
leaf blight
protein kinases
cell death
engineering
plasma membrane
oxygen
breeding
nitrogen
elicitors
proteins
cells

Keywords

  • Chimeric receptor
  • Chitin signal
  • Disease resistance
  • HR cell death
  • MAMP-induced resistance
  • Rice blast fungus

ASJC Scopus subject areas

  • Plant Science

Cite this

Kishimoto, K., Kouzai, Y., Kaku, H., Shibuya, N., Minami, E., & Nishizawa, Y. (2011). Enhancement of MAMP signaling by chimeric receptors improves disease resistance in plants. Plant Signaling and Behavior, 6(3), 449-451. https://doi.org/10.4161/psb.6.3.14655

Enhancement of MAMP signaling by chimeric receptors improves disease resistance in plants. / Kishimoto, Kyutaro; Kouzai, Yusuke; Kaku, Hanae; Shibuya, Naoto; Minami, Eiichi; Nishizawa, Yoko.

In: Plant Signaling and Behavior, Vol. 6, No. 3, 03.2011, p. 449-451.

Research output: Contribution to journalArticle

Kishimoto, K, Kouzai, Y, Kaku, H, Shibuya, N, Minami, E & Nishizawa, Y 2011, 'Enhancement of MAMP signaling by chimeric receptors improves disease resistance in plants', Plant Signaling and Behavior, vol. 6, no. 3, pp. 449-451. https://doi.org/10.4161/psb.6.3.14655
Kishimoto, Kyutaro ; Kouzai, Yusuke ; Kaku, Hanae ; Shibuya, Naoto ; Minami, Eiichi ; Nishizawa, Yoko. / Enhancement of MAMP signaling by chimeric receptors improves disease resistance in plants. In: Plant Signaling and Behavior. 2011 ; Vol. 6, No. 3. pp. 449-451.
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