Endovascular treatment for vasospasm after aneurysmal subarachnoid hemorrhage based on data of JR-NET3

JR-NET investigators

Research output: Contribution to journalArticle

Abstract

Endovascular treatments for vasospasm after subarachnoid hemorrhage are typically performed for patients who are refractory to recommended medical therapies. We analyzed the current status of endovascular treatments based on the data of Japanese Registry of Neuroendovascular Therapy (JR-NET)3, and evaluated factors related to improvement of imaging findings and neurological condition, and to mechanical hemorrhage complications. We collected data of 1211 treatments performed from 2010 to 2014. Target vessels for treatments were anterior circulation (n = 1079), posterior circulation (n = 91), and both (n = 32); the distribution of vasospasm was the proximal vessel (n = 754) to the Circle of Willis, distal vessel (n = 329), and both (n = 119). Of the treatments, 948 cases (78.3%) were intra-arterial administration of vasodilators and 259 (21.4%) were percutaneous transluminal angioplasty (PTA); 879 cases were the first intervention. The treatment time from onset was within 3 h in 378 (31.2%) cases, between 3 and 6 h in 349 (28.8%) cases, and over 6 h in 245 (20.2%) cases. The statistically significant factors associated with improvement on imaging findings was the first treatment, and treatment within 3 h from onset compared with that after 6 h. Additionally, the first and early treatments after the symptoms were associated with significantly improved neurological condition. All complications of mechanical hemorrhage occurred along with PTA. The findings show that endovascular treatment for vasospasm was effective, especially for cases who suffered from symptomatic vasospasm with a short interval after onset.

Original languageEnglish
Pages (from-to)495-502
Number of pages8
JournalNeurologia medico-chirurgica
Volume58
Issue number12
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Subarachnoid Hemorrhage
Therapeutics
Angioplasty
Hemorrhage
Circle of Willis
Vasodilator Agents
Registries

Keywords

  • Endovascular treatment
  • Neurological improvement
  • Vasospasm

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Endovascular treatment for vasospasm after aneurysmal subarachnoid hemorrhage based on data of JR-NET3. / JR-NET investigators.

In: Neurologia medico-chirurgica, Vol. 58, No. 12, 01.01.2018, p. 495-502.

Research output: Contribution to journalArticle

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AU - Iihara, Koji

AU - Ezura, Masayuki

AU - Hyodo, Akio

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AU - Nakahara, Ichiro

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