Endoscopic treatment for upper urinary tract urothelial carcinoma: Indication and outcome

Keiichiro Kawauchi, Shinya Uehara, Koichiro Wada, Yasuyuki Kobayashi, Katsumi Sasaki, Motoo Araki, Toyohiko Watanabe, Takashi Saika, Yasutomo Nasu, Hiromi Kumon, Koichi Monden, Noriaki Ono, Masaya Tsugawa

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Nephroureterectomy has been considered the "gold standard" of treatment for upper urinary tract urothelial carcinoma (UUT-UC). However, endoscopic treatment such as ureteroscopy, and percutaneous renal surgery has been generally accepted for patients requiring a nephron-sparing approach (i. e., solitary kidney or renal insufficiency) and for those with significant comorbidities precluding definitive surgery. With the development of flexible and durable ureteroscopes that have a smaller diameter, the rate of histological diagnosis has improved significantly. We herein review current reports and our own experience regarding the endoscopic management of UUT-UC. Endoscopic management is a safe and effective treatment alternative to nephroureterectomy in the management of UUT-UC. Survival outcomes are comparable, but renal preservation therapy offers the advantage of reduced morbidity, fewer complications, and the potential for a better quality of life. However, recurrence and disease progression are not uncommon and underscore the need for strict tumor surveillance.

Original languageEnglish
Pages (from-to)599-604
Number of pages6
JournalNishinihon Journal of Urology
Volume74
Issue number11
Publication statusPublished - Nov 1 2012

Keywords

  • Endoscopic treatment
  • Minimum invasive treatment
  • Nephrou-sparing approach
  • Upper urinary tract urothelial carcinoma

ASJC Scopus subject areas

  • Urology

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