Endobronchial ultrasound-guided transbronchial biopsy with or without a guide sheath for diagnosis of lung Cancer

Daisuke Minami, Nagio Takigawa, Daisuke Morichika, Toshio Kubo, Kadoaki Oohashi, Akiko Sato, Katsuyuki Hotta, Masahiro Tabata, Mitsune Tanimoto, Katsuyuki Kiura

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Endobronchial ultrasound-guided transbronchial biopsy with a guide sheath (EBUS-GS) is widely used for diagnosing lung cancers; however, the diagnostic yield varies widely. This study aimed to assess the efficiency of EBUS-GS. Methods: We retrospectively evaluated the results of 110 patients who underwent transbronchial biopsy (TBB) for diagnosis of peripheral lung cancer. Bronchoscopy with and without EBUS-GS was performed in 60 (group A) and 50 patients (group B), respectively; their medical records were examined, and results from the two groups were compared by using the unpaired Student t-test. Results: The diagnostic sensitivity for lung cancer was 83.3% in group A and 68% in group B ( P=0.066) while using at least one of the following procedures: TBB, cytological brushing, and bronchial washing. The diagnostic sensitivity for lesions ≥20. mm was 86.4% in group A and 76.7% in group B ( P=0.263). Moreover, the diagnostic sensitivity for lesions 10-20. mm was 60% in group A and 14.2% in group B ( P=0.0004); the diagnostic sensitivity with TBB alone was 63.3% in group A and 44% in group B ( P=0.043). The diagnostic sensitivity with TBB alone for lesions ≥20. mm was 70.2% in group A and 44.8% in group B ( P=0.051). Moreover, the diagnostic sensitivity for lesions 10-20. mm in size was 45% in group A and 14.2% in group B with TBB alone ( P=0.115). Conclusion: EBUS-GS with TBB, brushing, and bronchial washing is effective in diagnosing lung cancers sized

Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalRespiratory Investigation
Volume53
Issue number3
DOIs
Publication statusPublished - May 1 2015

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Lung Neoplasms
Biopsy
Bronchoscopy
Medical Records
Students

Keywords

  • Bronchoscopy
  • Endobronchial ultrasound-guided transbronchial biopsy
  • Guide sheath
  • Lung cancer

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Endobronchial ultrasound-guided transbronchial biopsy with or without a guide sheath for diagnosis of lung Cancer. / Minami, Daisuke; Takigawa, Nagio; Morichika, Daisuke; Kubo, Toshio; Oohashi, Kadoaki; Sato, Akiko; Hotta, Katsuyuki; Tabata, Masahiro; Tanimoto, Mitsune; Kiura, Katsuyuki.

In: Respiratory Investigation, Vol. 53, No. 3, 01.05.2015, p. 93-97.

Research output: Contribution to journalArticle

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abstract = "Background: Endobronchial ultrasound-guided transbronchial biopsy with a guide sheath (EBUS-GS) is widely used for diagnosing lung cancers; however, the diagnostic yield varies widely. This study aimed to assess the efficiency of EBUS-GS. Methods: We retrospectively evaluated the results of 110 patients who underwent transbronchial biopsy (TBB) for diagnosis of peripheral lung cancer. Bronchoscopy with and without EBUS-GS was performed in 60 (group A) and 50 patients (group B), respectively; their medical records were examined, and results from the two groups were compared by using the unpaired Student t-test. Results: The diagnostic sensitivity for lung cancer was 83.3{\%} in group A and 68{\%} in group B ( P=0.066) while using at least one of the following procedures: TBB, cytological brushing, and bronchial washing. The diagnostic sensitivity for lesions ≥20. mm was 86.4{\%} in group A and 76.7{\%} in group B ( P=0.263). Moreover, the diagnostic sensitivity for lesions 10-20. mm was 60{\%} in group A and 14.2{\%} in group B ( P=0.0004); the diagnostic sensitivity with TBB alone was 63.3{\%} in group A and 44{\%} in group B ( P=0.043). The diagnostic sensitivity with TBB alone for lesions ≥20. mm was 70.2{\%} in group A and 44.8{\%} in group B ( P=0.051). Moreover, the diagnostic sensitivity for lesions 10-20. mm in size was 45{\%} in group A and 14.2{\%} in group B with TBB alone ( P=0.115). Conclusion: EBUS-GS with TBB, brushing, and bronchial washing is effective in diagnosing lung cancers sized",
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AU - Kubo, Toshio

AU - Oohashi, Kadoaki

AU - Sato, Akiko

AU - Hotta, Katsuyuki

AU - Tabata, Masahiro

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AU - Kiura, Katsuyuki

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