Enantioselective Denitrogenative Annulation of 1H-Tetrazoles with Styrenes Catalyzed by Rhodium

Takayuki Nakamuro, Kohei Hagiwara, Tomoya Miura, Masahiro Murakami

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Sulfonylation of 1H-tetrazoles with triflic anhydride in the presence of chiral rhodium(II) carboxylate dimers causes denitrogenation to generate α-azo rhodium(II) carbenoid species as new types of donor/acceptor carbenoids, which then readily react with styrenes to afford 3,5-diaryl-2-pyrazolines with a high degree of enantioselectivity.

Original languageEnglish
Pages (from-to)5497-5500
Number of pages4
JournalAngewandte Chemie - International Edition
Volume57
Issue number19
DOIs
Publication statusPublished - May 4 2018
Externally publishedYes

Keywords

  • annulation
  • asymmetric catalysis
  • carbenoids
  • rhodium
  • tetrazoles

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint

Dive into the research topics of 'Enantioselective Denitrogenative Annulation of 1H-Tetrazoles with Styrenes Catalyzed by Rhodium'. Together they form a unique fingerprint.

Cite this