Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India

Gopinath Balakrish Nair, Thandavarayan Ramamurthy, Mihir Kumar Bhattacharya, Triveni Krishnan, Sandipan Ganguly, Dhira Rani Saha, Krishnan Rajendran, Byomkesh Manna, Mrinmoy Ghosh, Keinosuke Okamoto, Yoshifumi Takeda

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Abstract. Background. This study was conducted to determine the etiology of diarrhoea in a hospital setting in Kolkata. Active surveillance was conducted for 2 years on two random days per week by enrolling every fifth diarrhoeal patient admitted to the Infectious Diseases and Beliaghata General Hospital in Kolkata. Results. Most of the patients (76.1%) had acute watery diarrhoea in association with vomiting (77.7%) and some dehydration (92%). Vibrio cholerae O1, Rotavirus and Giardia lamblia were the important causes of diarrhoea. Among Shigella spp, S. flexneri 2a and 3a serotypes were most predominantly isolated. Enteric viruses, EPEC and EAEC were common in children <5 year age group. Atypical EPEC was comparatively higher than the typical EPEC. Multidrug resistance was common among V. cholerae O1 and Shigella spp including tetracycline and ciprofloxacin. Polymicrobial infections were common in all age groups and 27.9% of the diarrhoea patients had no potential pathogen. Conclusions. Increase in V. cholerae O1 infection among <2 years age group, resistance of V. cholerae O1 to tetracycline, rise of untypable S. flexnerii, higher proportion of atypical EPEC and G. lamblia and polymicrobial etiology are some of the emerging trends observed in this diarrhoeal disease surveillance.

Original languageEnglish
Article number4
JournalGut Pathogens
Volume2
Issue number1
DOIs
Publication statusPublished - 2010

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Vibrio cholerae O1
Enteropathogenic Escherichia coli
India
Diarrhea
Giardia lamblia
Shigella
Age Groups
Tetracycline
Enterovirus
Rotavirus
Multiple Drug Resistance
Ciprofloxacin
Coinfection
Dehydration
General Hospitals
Vomiting
Communicable Diseases
Infection

ASJC Scopus subject areas

  • Gastroenterology
  • Infectious Diseases
  • Microbiology
  • Parasitology

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Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India. / Nair, Gopinath Balakrish; Ramamurthy, Thandavarayan; Bhattacharya, Mihir Kumar; Krishnan, Triveni; Ganguly, Sandipan; Saha, Dhira Rani; Rajendran, Krishnan; Manna, Byomkesh; Ghosh, Mrinmoy; Okamoto, Keinosuke; Takeda, Yoshifumi.

In: Gut Pathogens, Vol. 2, No. 1, 4, 2010.

Research output: Contribution to journalArticle

Nair, GB, Ramamurthy, T, Bhattacharya, MK, Krishnan, T, Ganguly, S, Saha, DR, Rajendran, K, Manna, B, Ghosh, M, Okamoto, K & Takeda, Y 2010, 'Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India', Gut Pathogens, vol. 2, no. 1, 4. https://doi.org/10.1186/1757-4749-2-4
Nair, Gopinath Balakrish ; Ramamurthy, Thandavarayan ; Bhattacharya, Mihir Kumar ; Krishnan, Triveni ; Ganguly, Sandipan ; Saha, Dhira Rani ; Rajendran, Krishnan ; Manna, Byomkesh ; Ghosh, Mrinmoy ; Okamoto, Keinosuke ; Takeda, Yoshifumi. / Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India. In: Gut Pathogens. 2010 ; Vol. 2, No. 1.
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AU - Bhattacharya, Mihir Kumar

AU - Krishnan, Triveni

AU - Ganguly, Sandipan

AU - Saha, Dhira Rani

AU - Rajendran, Krishnan

AU - Manna, Byomkesh

AU - Ghosh, Mrinmoy

AU - Okamoto, Keinosuke

AU - Takeda, Yoshifumi

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