Emergency caesarean section saved both an anti-musk antibody-positive myasthenia gravis mother with pregnancy-induced hypertension and her premature baby

Yoshiaki Takahashi, Toru Yamashita, Ryuta Morihara, Yumiko Nakano, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Kei Hayata, Hisashi Masuyama, Tomoka Okamura, Yousuke Washio, Koji Abe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 5 days of pregnancy, and who underwent an emergency caesarean section (CS). Her MG symptoms gradually improved in the subsequent weeks. The premature baby with positive MuSK antibodies was successfully delivered, but the male baby required temporary artificial ventilation. However, his condition also gradually improved over time. The present case suggests that an emergency CS could rescue both the mother, who was in critical condition, and the prematurely born baby, even when suffering from acute respiratory insufficiency.

Original languageEnglish
Pages (from-to)3361-3364
Number of pages4
JournalInternal Medicine
Volume56
Issue number24
DOIs
Publication statusPublished - Jan 1 2017

Fingerprint

Pregnancy Induced Hypertension
Myasthenia Gravis
Cesarean Section
Respiratory Insufficiency
Anti-Idiotypic Antibodies
Emergencies
Phosphotransferases
Mothers
Muscles
Antibodies
Pregnant Women
Pregnancy
musk

Keywords

  • Anti-MuSK antibody
  • Emergency caesarean section
  • Myasthenia gravis
  • Pregnancy-induced hypertension
  • Premature baby

ASJC Scopus subject areas

  • Internal Medicine

Cite this

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abstract = "We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 5 days of pregnancy, and who underwent an emergency caesarean section (CS). Her MG symptoms gradually improved in the subsequent weeks. The premature baby with positive MuSK antibodies was successfully delivered, but the male baby required temporary artificial ventilation. However, his condition also gradually improved over time. The present case suggests that an emergency CS could rescue both the mother, who was in critical condition, and the prematurely born baby, even when suffering from acute respiratory insufficiency.",
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AU - Takahashi, Yoshiaki

AU - Yamashita, Toru

AU - Morihara, Ryuta

AU - Nakano, Yumiko

AU - Sato, Kota

AU - Takemoto, Mami

AU - Hishikawa, Nozomi

AU - Ohta, Yasuyuki

AU - Hayata, Kei

AU - Masuyama, Hisashi

AU - Okamura, Tomoka

AU - Washio, Yousuke

AU - Abe, Koji

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AB - We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 5 days of pregnancy, and who underwent an emergency caesarean section (CS). Her MG symptoms gradually improved in the subsequent weeks. The premature baby with positive MuSK antibodies was successfully delivered, but the male baby required temporary artificial ventilation. However, his condition also gradually improved over time. The present case suggests that an emergency CS could rescue both the mother, who was in critical condition, and the prematurely born baby, even when suffering from acute respiratory insufficiency.

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KW - Myasthenia gravis

KW - Pregnancy-induced hypertension

KW - Premature baby

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