Embedded TiO 2 waveguides for sensing nanofluorophores in a microfluidic channel

Masayuki Furuhashi; Masazumi Fujiwara; Takahito Ohshiro; Kazuki Matsubara; Makusu Tsutsui; Masateru Taniguchi; Shigeki Takeuchi; Tomoji Kawai

doi:10.1063/1.4757759

Embedded TiO ₂ waveguides for sensing nanofluorophores in a microfluidic channel

Masayuki Furuhashi, Masazumi Fujiwara, Takahito Ohshiro, Kazuki Matsubara, Makusu Tsutsui, Masateru Taniguchi, Shigeki Takeuchi, Tomoji Kawai

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Crossed structure of a microfluidic channel and an optical channel waveguide is simple and promising to realize detection of weak fluorescence on an integrated device. Usage of TiO ₂ waveguides is suitable for the device because of the high numerical aperture. In this study, we developed fabrication processes for the TiO ₂ channel waveguides traversed by microfluidic channels of 0.5-6 μm widths and investigated the effect of the microfluidic channel to the transmittances. The results elucidated that the photointensity at the microfluidic channel was enough to excite fluorophores. Furthermore, we demonstrated detection of fluorescence from 350 quantum dots.

Original language	English
Article number	153115
Journal	Applied Physics Letters
Volume	101
Issue number	15
DOIs	https://doi.org/10.1063/1.4757759
Publication status	Published - Oct 8 2012
Externally published	Yes

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

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title = "Embedded TiO 2 waveguides for sensing nanofluorophores in a microfluidic channel",

abstract = "Crossed structure of a microfluidic channel and an optical channel waveguide is simple and promising to realize detection of weak fluorescence on an integrated device. Usage of TiO 2 waveguides is suitable for the device because of the high numerical aperture. In this study, we developed fabrication processes for the TiO 2 channel waveguides traversed by microfluidic channels of 0.5-6 μm widths and investigated the effect of the microfluidic channel to the transmittances. The results elucidated that the photointensity at the microfluidic channel was enough to excite fluorophores. Furthermore, we demonstrated detection of fluorescence from 350 quantum dots.",

author = "Masayuki Furuhashi and Masazumi Fujiwara and Takahito Ohshiro and Kazuki Matsubara and Makusu Tsutsui and Masateru Taniguchi and Shigeki Takeuchi and Tomoji Kawai",

note = "Funding Information: We would like to thank H. Kowada, T. Kawase, K. Konda, C. Hotehama, S. Murayama, and R. Yamada for their technical assistance. This research was supported by the Funding Program for World-Leading Innovative Research and Development on Science and Technology “Innovative NanoBiodevice based on Single Molecule Analysis” from the Japan Society for the Promotion of Science. Furuhashi acknowledges the support from KAKENHI (24710150).",

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doi = "10.1063/1.4757759",

language = "English",

volume = "101",

journal = "Applied Physics Letters",

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AU - Furuhashi, Masayuki

AU - Fujiwara, Masazumi

AU - Ohshiro, Takahito

AU - Matsubara, Kazuki

AU - Tsutsui, Makusu

AU - Taniguchi, Masateru

AU - Takeuchi, Shigeki

AU - Kawai, Tomoji

N1 - Funding Information: We would like to thank H. Kowada, T. Kawase, K. Konda, C. Hotehama, S. Murayama, and R. Yamada for their technical assistance. This research was supported by the Funding Program for World-Leading Innovative Research and Development on Science and Technology “Innovative NanoBiodevice based on Single Molecule Analysis” from the Japan Society for the Promotion of Science. Furuhashi acknowledges the support from KAKENHI (24710150).

PY - 2012/10/8

Y1 - 2012/10/8

N2 - Crossed structure of a microfluidic channel and an optical channel waveguide is simple and promising to realize detection of weak fluorescence on an integrated device. Usage of TiO 2 waveguides is suitable for the device because of the high numerical aperture. In this study, we developed fabrication processes for the TiO 2 channel waveguides traversed by microfluidic channels of 0.5-6 μm widths and investigated the effect of the microfluidic channel to the transmittances. The results elucidated that the photointensity at the microfluidic channel was enough to excite fluorophores. Furthermore, we demonstrated detection of fluorescence from 350 quantum dots.

AB - Crossed structure of a microfluidic channel and an optical channel waveguide is simple and promising to realize detection of weak fluorescence on an integrated device. Usage of TiO 2 waveguides is suitable for the device because of the high numerical aperture. In this study, we developed fabrication processes for the TiO 2 channel waveguides traversed by microfluidic channels of 0.5-6 μm widths and investigated the effect of the microfluidic channel to the transmittances. The results elucidated that the photointensity at the microfluidic channel was enough to excite fluorophores. Furthermore, we demonstrated detection of fluorescence from 350 quantum dots.

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Embedded TiO ₂ waveguides for sensing nanofluorophores in a microfluidic channel

Abstract

ASJC Scopus subject areas

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