Abstract
The kinetics of the hydride transfer reaction between Methylene Blue (MB+) and 1-benzyl-1,4-dihydronicotinamide (BNAH) were studied in 10% ethanol-90% water mixed solvents containing β- and γ-cyclodextrins (β-CD and γ-CD). The pseudo-first order rate constant shows kinetic saturation at high initial concentration of BNAH. This indicates the formation of a complex between MB+ and BNAH. The reaction was suppressed by addition of β-CD, but enhanced by addition of γ-CD. MB+ and BNAH were separately accommodated within the β-CD cavity and the cavity walls may protect the activity site of the reactants. On the other hand, in the MB+-BNAH-γ-CD system, the inclusion of the complex between MB+ and BNAH with γ-CD occurred. This effect of γ-CD can distinguish between the productive and non-productive nature of the complex.
| Original language | English |
|---|---|
| Pages (from-to) | 233-239 |
| Number of pages | 7 |
| Journal | Journal of Inclusion Phenomena |
| Volume | 54 |
| Issue number | 3-4 |
| DOIs | |
| Publication status | Published - Apr 2006 |
| Externally published | Yes |
Keywords
- 1-benzyl-1,4-dihydronicotinamide
- Cyclodextrin
- Hydride transfer reaction
- Inclusion complexes
- Methylene blue
- Reaction mechanism
ASJC Scopus subject areas
- Food Science
- Chemistry(all)
- Condensed Matter Physics