Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma

Hiromichi Yamane, Nobuaki Ochi, Takayuki Tabayashi, Lu Lu, Tomoko Yamagishi, Yasumasa Monobe, Takehiro Tanaka, Eisei Kondoh, Nagio Takigawa

Research output: Contribution to journalArticle

Abstract

A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.

Original languageEnglish
Pages (from-to)3213-3215
Number of pages3
JournalInternal Medicine
Volume51
Issue number22
DOIs
Publication statusPublished - Nov 28 2012

Keywords

  • Cervical cancer
  • Chronic lymph edema
  • Factor VIII-related antigen
  • Lymphangiosarcoma

ASJC Scopus subject areas

  • Internal Medicine

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    Yamane, H., Ochi, N., Tabayashi, T., Lu, L., Yamagishi, T., Monobe, Y., Tanaka, T., Kondoh, E., & Takigawa, N. (2012). Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma. Internal Medicine, 51(22), 3213-3215. https://doi.org/10.2169/internalmedicine.51.8083