Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma

Hiromichi Yamane, Nobuaki Ochi, Takayuki Tabayashi, Lu Lu, Tomoko Yamagishi, Yasumasa Monobe, Takehiro Tanaka, Eisei Kondoh, Nagio Takigawa

Research output: Contribution to journalArticle

Abstract

A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.

Original languageEnglish
Pages (from-to)3213-3215
Number of pages3
JournalInternal Medicine
Volume51
Issue number22
DOIs
Publication statusPublished - 2012

Fingerprint

Lymphangiosarcoma
Factor VIII
von Willebrand Factor
Hysterectomy
Palliative Care
Gait
Uterine Cervical Neoplasms
Reference Values
Radiotherapy
Referral and Consultation
Neoplasms

Keywords

  • Cervical cancer
  • Chronic lymph edema
  • Factor VIII-related antigen
  • Lymphangiosarcoma

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Yamane, H., Ochi, N., Tabayashi, T., Lu, L., Yamagishi, T., Monobe, Y., ... Takigawa, N. (2012). Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma. Internal Medicine, 51(22), 3213-3215. https://doi.org/10.2169/internalmedicine.51.8083

Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma. / Yamane, Hiromichi; Ochi, Nobuaki; Tabayashi, Takayuki; Lu, Lu; Yamagishi, Tomoko; Monobe, Yasumasa; Tanaka, Takehiro; Kondoh, Eisei; Takigawa, Nagio.

In: Internal Medicine, Vol. 51, No. 22, 2012, p. 3213-3215.

Research output: Contribution to journalArticle

Yamane, H, Ochi, N, Tabayashi, T, Lu, L, Yamagishi, T, Monobe, Y, Tanaka, T, Kondoh, E & Takigawa, N 2012, 'Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma', Internal Medicine, vol. 51, no. 22, pp. 3213-3215. https://doi.org/10.2169/internalmedicine.51.8083
Yamane, Hiromichi ; Ochi, Nobuaki ; Tabayashi, Takayuki ; Lu, Lu ; Yamagishi, Tomoko ; Monobe, Yasumasa ; Tanaka, Takehiro ; Kondoh, Eisei ; Takigawa, Nagio. / Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma. In: Internal Medicine. 2012 ; Vol. 51, No. 22. pp. 3213-3215.
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