Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma

Hiromichi Yamane; Nobuaki Ochi; Takayuki Tabayashi; Lu Lu; Tomoko Yamagishi; Yasumasa Monobe; Takehiro Tanaka; Eisei Kondoh; Nagio Takigawa

doi:10.2169/internalmedicine.51.8083

Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma

Hiromichi Yamane, Nobuaki Ochi, Takayuki Tabayashi, Lu Lu, Tomoko Yamagishi, Yasumasa Monobe, Takehiro Tanaka, Eisei Kondoh, Nagio Takigawa

Research output: Contribution to journal › Article › peer-review

Abstract

A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.

Original language	English
Pages (from-to)	3213-3215
Number of pages	3
Journal	Internal Medicine
Volume	51
Issue number	22
DOIs	https://doi.org/10.2169/internalmedicine.51.8083
Publication status	Published - 2012

Keywords

Cervical cancer
Chronic lymph edema
Factor VIII-related antigen
Lymphangiosarcoma

ASJC Scopus subject areas

Internal Medicine

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title = "Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma",

abstract = "A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.",

keywords = "Cervical cancer, Chronic lymph edema, Factor VIII-related antigen, Lymphangiosarcoma",

author = "Hiromichi Yamane and Nobuaki Ochi and Takayuki Tabayashi and Lu Lu and Tomoko Yamagishi and Yasumasa Monobe and Takehiro Tanaka and Eisei Kondoh and Nagio Takigawa",

year = "2012",

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T1 - Elevated coagulation factor VIII plasma activity in a patient with lymphangiosarcoma

AU - Yamane, Hiromichi

AU - Ochi, Nobuaki

AU - Tabayashi, Takayuki

AU - Lu, Lu

AU - Yamagishi, Tomoko

AU - Monobe, Yasumasa

AU - Tanaka, Takehiro

AU - Kondoh, Eisei

AU - Takigawa, Nagio

PY - 2012

Y1 - 2012

N2 - A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.

AB - A 72-year-old woman was referred to our hospital for palliative care. Fifteen years earlier, she had undergone total hysterectomy and radiotherapy for cervical cancer. One year before her referral, she visited a hospital due to a gait disturbance and was diagnosed with lymphangiosarcoma. The level of coagulation factor VIII plasma activity was >201% (normal range: 62-145%) and the immunohistochemical results were positive for factor VIII-related antigen in a tumor specimen. To the best of our knowledge, this is the first report of high coagulation factor VIII plasma activity in a patient with lymphangiosarcoma.

KW - Cervical cancer

KW - Chronic lymph edema

KW - Factor VIII-related antigen

KW - Lymphangiosarcoma

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